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Saline (0.9%, sterile, for infusion)

DRUG8 trials

Sponsors

Stealth BioTherapeutics Inc., Qingyuan Zhan, Ricardo Mora, HTIC, Inc, Rutgers, The State University of New Jersey

Conditions

ARDS (Acute Respiratory Distress Syndrome)Adenovirus Infections, HumanAntibiotic Prophylaxis SurgeryExerciseHealthy VolunteersHyperlactatemiaInfluenzaLipolysis

Phase 1

Study to Assess the Pharmacodynamic Effects of Unfractionated Heparin (UFH) in Healthy Volunteers With and Without Bendavia
CompletedNCT01513200
Stealth BioTherapeutics Inc.Healthy Volunteers
Start: 2012-01-31End: 2012-02-29Updated: 2012-04-19
Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HT31-1 for Treating ARDS
RecruitingNCT07449572
HTIC, IncARDS (Acute Respiratory Distress Syndrome)
Start: 2026-05-01End: 2026-11-01Target: 24Updated: 2026-05-22

Phase 3

Adaptive RCT of Corticosteroids for Severe Adenovirus Pneumonia in Adults
Not yet recruitingNCT07152600
Qingyuan ZhanAdenovirus Infections, Human
Start: 2026-02-01End: 2027-12-31Target: 262Updated: 2026-01-21
Corticosteroids for PJP in Non-HIV Immunocompromised Adults
Not yet recruitingNCT07152613
Qingyuan ZhanPneumocystis Jiroveci Pneumonia
Start: 2025-09-08End: 2027-12-31Target: 240Updated: 2025-09-09
Adaptive RCT of Corticosteroids for Severe Influenza Pneumonia in Adults
Not yet recruitingNCT07351500
Qingyuan ZhanInfluenza
Start: 2026-01-15End: 2028-11-30Target: 496Updated: 2026-01-20
Adaptive RCT of Corticosteroids for Severe Chlamydia Psittaci Pneumonia in Adults
Not yet recruitingNCT07352865
Qingyuan ZhanPsittacosis
Start: 2026-01-15End: 2028-11-30Target: 100Updated: 2026-01-20

Phase 4

Efficacy and Safety of Intraosseous Antibiotic Prophylaxis in Total Hip Replacement
Enrolling by invitationNCT07549542
Rutgers, The State University of New JerseyAntibiotic Prophylaxis Surgery
Start: 2025-10-20End: 2026-11-01Target: 25Updated: 2026-04-29

Unknown Phase

Role of Elevated Lactate Levels on Lipid and Carbohydrate Metabolism.
RecruitingNCT07426172
Ricardo MoraExercise, Hyperlactatemia, Lipolysis +1
Start: 2026-01-20End: 2028-09-30Target: 24Updated: 2026-02-23