sac-TMT

BIOLOGICAL2 trials

Sponsors

Merck Sharp & Dohme LLC, Second Affiliated Hospital, School of Medicine, Zhejiang University

Conditions

NSCLCNeuroendocrine Neoplasms (Tumours)Non-small Cell Lung Cancer

Phase 2

The Efficacy of TROP2-ADC in Advanced Extrapulmonary High-Grade Neuroendocrine Neoplasms Failure of Standard Therapy

Not yet recruitingNCT07077564

Second Affiliated Hospital, School of Medicine, Zhejiang UniversityNeuroendocrine Neoplasms (Tumours)

Start: 2025-07-20End: 2028-07-20Target: 35Updated: 2025-07-22

Phase 3

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

RecruitingNCT06422143

Merck Sharp & Dohme LLCNon-small Cell Lung Cancer, NSCLC

Start: 2024-06-10End: 2031-08-15Target: 851Updated: 2026-09-03