S-1 80mg/m2/day for 14 days plus L-OHP 100mg/m2 on day 1 every 21 days is administered for 3 course. After treatment, response rate is evaluated. Surgical operation is performed.
Sponsors
Niigata Colorectal cancer Chemotherapy Study Group (NCCSG), Niigata Colorectal cancer Chemotherapy Study Group (NCCSG)
Conditions
locally advanced colorectal cancer with lymph node metastaseslocally advanced rectal cancer
Phase 2
Phase II study of neoadjuvant chemotherapy with L-OHP and S-1 for locally advanced colorectal cancer with lymph node metastases
Active, not recruitingJPRN-UMIN000003529
Start: 2010-04-01Target: 35Updated: 2026-06-29
Phase II study of neoadjuvant chemotherapy with L-OHP and S-1 for locally advanced rectal cancer (NCCSG-09)
Active, not recruitingJPRN-UMIN000009764
Start: 2013-01-15Target: 35Updated: 2026-06-29