RYZ101
Sponsors
Rayzebio Inc., RayzeBio, Inc.
Conditions
Advanced Breast CancerCarcinoidCarcinoid TumorER+ Breast CancerGEP-NETGastroenteropancreatic Neuroendocrine TumorGastroenteropancreatic Neuroendocrine Tumor DiseaseHER2-negative Breast Cancer
Phase 1
Phase 3
Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy
RecruitingNCT05477576
Start: 2022-03-24End: 2030-12-01Target: 338Updated: 2026-03-30
Trial title: Phase 1b/3 global, randomized, controlled, open-label trial comparing treatment with RYZ101 to standard of care (SoC) therapy in subjects with inoperable, advanced, somatostatin receptor expressing (SSTR+), well-differentiated gastro-enteropancreatic neuroendocrine tumors (GEP-NETs) that have progressed following prior 177Lu-labelled somatostatin analogue (177Lu-SSA) therapy (ACTION-1)
RecruitingCTIS2023-509334-19-00
Start: 2024-10-17Target: 78Updated: 2025-08-22