rVIII-SingleChain

BIOLOGICAL3 trials

Sponsors

CSL Behring

Conditions

Congenital Hemophilia AHemophilia ASevere Hemophilia A

Phase 2

An Open-label Safety, Efficacy and Pharmacokinetic Study of a Recombinant FVIII Compared to Recombinant Human Antihemophilic FVIII in Patients With Severe Hemophilia A

CompletedNCT01486927

CSL BehringHemophilia A

Start: 2012-02-29End: 2014-12-31Updated: 2016-08-09

Phase 3

Pharmacokinetic, Efficacy, and Safety Study of Recombinant Factor VIII Single Chain (rVIII-SingleChain) in Children With Severe Hemophilia A

CompletedNCT02093897

CSL BehringCongenital Hemophilia A

Start: 2014-03-31End: 2015-08-31Updated: 2017-01-27

An Open-label Safety and Efficacy Study of Recombinant FVIII in Patients With Severe Hemophilia A

CompletedNCT02172950

CSL BehringHemophilia A, Severe Hemophilia A

Start: 2014-10-13End: 2021-01-19Updated: 2021-10-27

Related Papers

Efficacy and safety of rVIII-SingleChain: results of a phase 1/3 multicenter clinical trial in severe hemophilia A

Blood2016-06-2385 citations