Ruxience 500 mg concentrate for solution for infusion
Sponsors
University Hospital Of Ulm AöR, Merck Sharp & Dohme LLC, Amsterdam UMC, Janssen - Cilag International, UZ Leuven
Conditions
Large B-cell LymphomaMental DisorderMultiple sclerosisMyasthenia gravisRelapsed or Refractory Diffuse Large B-Cell LymphomaRelapsed/Refractory Mantle Cell LymphomaRheumatoid arthritisWaldenström’s Macroglobulinemia
Phase 2
A Phase 2/3 Multicenter, Open-label, Randomized, Active-Control Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (waveLINE-003)
RecruitingCTIS2022-502646-27-00
Start: 2022-06-24Target: 35Updated: 2025-11-17
A Randomized, Controlled, Open-label, Multicenter, Inferentially Seamless Phase 2/3 Study of Ibrutinib in Combination With Rituximab Versus Physician’s Choice of Lenalidomide Plus Rituximab or Bortezomib Plus Rituximab in Participants with Relapsed or Refractory Mantle Cell Lymphoma
CompletedCTIS2023-503618-64-00
Start: 2022-11-16End: 2024-09-18Target: 7Updated: 2024-04-24
Efficacy of Venetoclax in combination with Rituximab in Waldenström’s Macroglobulinemia
RecruitingCTIS2022-500574-34-00
Start: 2025-03-21Target: 55Updated: 2025-11-12
Phase 3
Immediate corticosteroid therapy and rituximab to prevent generalization in ocular myasthenia gravis: a PROBE-type multicenter, open-label, randomized controlled trial
RecruitingCTIS2023-506656-24-00
Start: 2025-02-12Target: 128Updated: 2025-06-06
Danish non-inferiority study of ocrelizumab and rituximab in MS: A randomized study comparing the efficacy of ocrelizumab
and rituximab in active multiple sclerosis
Active, not recruitingCTIS2024-514287-84-00
Start: 2021-04-28Target: 600Updated: 2024-08-05
Phase III randomized, multicenter open label clinical trial to evaluate the efficacy of immunomodulatory therapy in case of psychiatric disorders with proven dysimmunity. TIM-DePisT
RecruitingCTIS2024-518259-49-00
Start: 2024-07-04Target: 1000Updated: 2025-10-03
A Phase III, Multicentre, Open-Label, Randomised Study Evaluating the Efficacy and Safety of R-mini-CHOP x2 followed by AZD0486 versus R-mini-CHOP x6 in Elderly or Unfit Participants with Newly Diagnosed Large B-cell Lymphoma (SOUNDTRACK-D2)
Not yet recruitingCTIS2025-522029-37-00
Target: 14Updated: 2026-01-30
Phase 4
Noisy Rebels; Non-inferiority study of rituximab compared to ocrelizumab in relapsing MS
Active, not recruitingCTIS2022-502664-21-00
Start: 2023-05-01Target: 200Updated: 2025-10-14
Tapering of Rituximab Based on Interval Prolongation Compared to Disease Activity-Guided Dose Reduction in Patients with Rheumatoid Arthritis: The RITUXERA Trial.
RecruitingCTIS2023-506638-59-01
Start: 2024-01-09Target: 134Updated: 2025-08-27