Rusfertide

DRUG3 trials

Sponsors

Protagonist Therapeutics, Inc., Takeda

Conditions

Polycythemia Vera

Phase 2

A Study of Rusfertide in Japanese Adults With Polycythemia Vera

RecruitingNCT07648030

TakedaPolycythemia Vera

Start: 2026-07-14End: 2030-05-17Target: 9Updated: 2026-09-02

A Study of Rusfertide in Adults With Polycythemia Vera in China

Not yet recruitingNCT07765602

TakedaPolycythemia Vera

Start: 2027-03-01End: 2028-08-01Target: 24Updated: 2026-08-28

Phase 3

A Phase 3 Study of Rusfertide in Patients With Polycythemia Vera

Active, not recruitingNCT05210790

Protagonist Therapeutics, Inc.Polycythemia Vera

Start: 2022-04-01End: 2027-06-30Updated: 2025-08-07

Related Papers

Rusfertide or placebo plus current standard-of-care therapy for polycythemia vera: Durability of response and safety results through week 52 from the randomized controlled phase 3 VERIFY study

Blood2025-11-03

Comprehensive analyses of patient-reported outcomes from the phase 3 VERIFY study of rusfertide or placebo plus current standard of care for polycythemia vera

Blood2025-11-03

Should dermatologic examinations become routine standard of care in patients with polycythemia vera? Observations from the phase 3 VERIFY study prior to rusfertide exposure

Blood2025-11-03

Results from VERIFY, a phase 3, double-blind, placebo (PBO)-controlled study of rusfertide for treatment of polycythemia vera (PV).

Journal of Clinical Oncology2025-06-042 citations

Final Results from the Phase 2 Revive Study Investigating the Hepcidin Mimetic Rusfertide in Patients with Polycythemia Vera (PV)

Blood2024-11-052 citations

VERIFY: A randomized controlled phase 3 study of the hepcidin mimetic rusfertide (PTG-300) in patients with polycythemia vera (PV).

Journal of Clinical Oncology2024-06-013 citations

Hepcidin mimetics in polycythemia vera: resolving the irony of iron deficiency and erythrocytosis.

2022-12-2916 citations

Verify: A Phase 3 Study of the Hepcidin Mimetic Rusfertide (PTG-300) in Patients with Polycythemia Vera

Blood2022-11-157 citations