Rovalpituzumab tesirine
Sponsors
AbbVie, Stemcentrx
Conditions
Advanced Solid TumorsCancerGlioblastomaHigh Grade Gastroenteropancreatic Neuroendocrine CarcinomaLarge-Cell Neuroendocrine CarcinomaMalignant MelanomaMedullary Thyroid CancerNeuroendocrine Prostate Cancer
Phase 1
Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors
TerminatedNCT02709889
Start: 2016-09-23End: 2019-08-27Updated: 2020-10-19
A Study of Rovalpituzumab Tesirine (SC16LD6.5) in the Frontline Treatment of Patients With Extensive Stage Small Cell Lung Cancer
TerminatedNCT02819999
Start: 2016-10-31End: 2019-05-31Updated: 2020-03-12
A Study of Rovalpituzumab Tesirine to Study Cardiac Ventricular Repolarization in Subjects With Small Cell Lung Cancer
CompletedNCT02874664
Start: 2016-09-30End: 2018-09-12Updated: 2018-09-24
A Study of Budigalimab (ABBV-181) in Participants With Advanced Solid Tumors
CompletedNCT03000257
Start: 2016-12-14End: 2022-03-29Updated: 2022-04-14
A Study of Rovalpituzumab Tesirine Administered in Combination With Nivolumab and With or Without Ipilimumab for Adults With Extensive-Stage Small Cell Lung Cancer
TerminatedNCT03026166
Start: 2017-03-30End: 2019-07-03Updated: 2020-07-17
A Study on the Safety and Tolerability of Rovalpituzumab Tesirine in Japanese Patients With Advanced, Recurrent Small Cell Lung Cancer
CompletedNCT03086239
Start: 2017-04-28End: 2018-08-20Updated: 2021-08-03
Phase 2
Study of Rovalpituzumab Tesirine (SC16LD6.5) for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Delta-Like Protein 3-Expressing Small Cell Lung Cancer
CompletedNCT02674568
Start: 2016-01-25End: 2018-10-19Updated: 2021-07-30
A Long-Term Study of Rovalpituzumab Tesirine
CompletedNCT03543358
Start: 2018-09-10End: 2019-11-26Updated: 2021-01-05
Phase 3
A Study of Rovalpituzumab Tesirine as Maintenance Therapy Following First- Line Platinum-Based Chemotherapy in Participants With Extensive Stage Small Cell Lung Cancer (MERU)
TerminatedNCT03033511
Start: 2017-02-07End: 2019-11-20Updated: 2021-07-29
Study Comparing Rovalpituzumab Tesirine Versus Topotecan in Subjects With Advanced or Metastatic Small Cell Lung Cancer With High Levels of Delta-like Protein 3 (DLL3) and Who Have First Disease Progression During or Following Front-line Platinum-based Chemotherapy (TAHOE)
CompletedNCT03061812
Start: 2017-04-11End: 2020-02-12Updated: 2021-02-23
Study Evaluating the Safety of Rovalpituzumab Tesirine for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Small Cell Lung Cancer
WithdrawnNCT03334487
Start: 2018-03-15End: 2018-12-20Updated: 2018-12-26
Unknown Phase
Related Papers
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