Routine blood pressure management

PROCEDURE5 trials

Sponsors

Peking University First Hospital, The University of Texas Health Science Center, Houston, Nanfang Hospital, Southern Medical University

Conditions

Abdominal SurgeryBlood PressureDexmedetomidineHigh-risk PatientsHypotensionMajor SurgeryPostoperative Complications

Phase 4

Intraoperative Goal-directed Blood Pressure and Dexmedetomidine on Outcomes

CompletedNCT03933306

Peking University First HospitalAbdominal Surgery, Blood Pressure, Dexmedetomidine +2

Start: 2019-05-20End: 2024-05-30Updated: 2025-07-18

The GUARDIAN Trial - Vasopressor Sub-Study

Enrolling by invitationNCT04934748

The University of Texas Health Science Center, HoustonBlood Pressure

Start: 2021-07-25End: 2027-04-25Target: 6254Updated: 2025-08-29

The GUARDIAN Trial - Induction Agent Sub-Study

Enrolling by invitationNCT04934683

The University of Texas Health Science Center, HoustonMajor Surgery

Start: 2021-07-25End: 2027-04-25Target: 6254Updated: 2025-08-29

Unknown Phase

The GUARDIAN Trial

RecruitingNCT04884802

The University of Texas Health Science Center, HoustonBlood Pressure

Start: 2021-07-25End: 2027-04-25Target: 6254Updated: 2025-08-29

PeRsonalized Blood prEssure Management on Postoperative Complications and Mortality in hIgh-risk Patients Undergoing Major Non-cardiac Surgery

RecruitingNCT06952387

Nanfang Hospital, Southern Medical UniversityHypotension

Start: 2025-06-03End: 2028-12-31Target: 1624Updated: 2025-07-14