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DRUG12 trials

Sponsors

Aarhus University Hospital, Orexa B.V., Viiv Healthcare UK Limited, NewAmsterdam Pharma B.V., Harmony Biosciences LLC

Conditions

COGNITIVE IMPAIRMENT ASSOCIATED WITH POST-COVID-19 SYNDROMEHIV InfectionsHypothyroidism Triiodothyronine Quality of Life Persistant complaintsKidney transplant recipientsKnee osteoarthritisMigrainePrader-Willi syndromeProgressive multiple sclerosis

Phase 1

Phase 2

Thiamine against chronic rheumatoid arthritis fatigue
CompletedCTIS2022-500922-13-00
Aarhus University HospitalRheumatoid Arthritis
Start: 2023-02-16End: 2023-08-30Target: 40Updated: 2023-03-03
A multi-center, randomized, double blind, placebo-controlled, phase 2 pilot efficacy study to investigate the efficacy of oral lidocaine (ORE-001) in preventing gastrointestinal disturbance/intolerance in patients after longitudinal laparotomy
CompletedCTIS2022-503113-31-01
Orexa B.V.longitudinal laparotomy
Start: 2023-12-19End: 2025-06-24Target: 126Updated: 2025-02-12
A Randomized, Double-Blind (Sponsor-Unblinded), Placebo-Controlled, Adaptive Study to Investigate the Antiviral Effect, Safety, Tolerability and Pharmacokinetics of VH3739937 in Treatment-Naïve Adults Living with HIV-1
CompletedCTIS2023-505780-37-00
Viiv Healthcare UK LimitedHIV Infections
Start: 2023-12-21End: 2025-03-17Target: 18Updated: 2024-11-22
Prospective, randomized, double-blind, placebo-controlled, single-center comparative trial evaluating oral Istradefylline 40 mg once daily for reducing microglial activation in the brain of patients with progressive multiple sclerosis (MS)
RecruitingCTIS2024-517336-21-00
University Of TurkuProgressive multiple sclerosis
Start: 2025-03-31Target: 34Updated: 2025-02-12
A RANDOMIZED, PLACEBO-CONTROLLED, TRIPLE-BLIND CLINICAL TRIAL TO INVESTIGATE TREATMENT EFFECTS AND SAFETY OF GINKGO BILOBA EXTRACT EGB 761® IN PARTICIPANTS WITH COGNITIVE IMPAIRMENT ASSOCIATED WITH POST-COVID-19 SYNDROME
Active, not recruitingCTIS2024-517199-39-00
Dr. Willmar Schwabe GmbH & Co. KGCOGNITIVE IMPAIRMENT ASSOCIATED WITH POST-COVID-19 SYNDROME
Start: 2025-03-19Target: 400Updated: 2026-01-19
A placebo controlled, randomized, double-blind, dose titration phase 2, safety and efficacy study of ORE-001 (oral lidocaine) in underweight elderly participants
RecruitingCTIS2024-516958-22-00
Orexa B.V.Underweight
Start: 2025-02-17Target: 60Updated: 2025-02-12
SGL-TX-PTDM: SGLT2i effect on PTDM development and kidney allograft function in kidney transplant recipients: A randomized, double-blind, placebo controlled, national multicenter trial
Not yet recruitingCTIS2024-518774-14-00
Odense University HospitalKidney transplant recipients
Target: 184Updated: 2026-03-09

Phase 3

Phase 4