Rotavirus vaccine

BIOLOGICAL14 trials

Sponsors

Butantan Institute, Sanofi Pasteur, a Sanofi Company, Merck Sharp & Dohme LLC, PATH, MCM Vaccines B.V.

Conditions

Bacterial InfectionsDiarrhoeal DiseaseHealthy VolunteersHealthy Volunteers (Meningococcal Infection)Immunity to Oral Polio VaccineImmunity to Oral Rotavirus VaccineInfectious DiseasesMeningitis

Phase 1

Rotavirus Vaccine Produced by Butantan Institute

CompletedNCT00981669

Butantan InstituteRotavirus Infections

Start: 2009-03-31End: 2010-06-30Updated: 2013-04-25

Safety and Immunogenicity of an Investigational Pentavalent Meningococcal ABCYW Vaccine Against Meningococcal Disease in Children, Toddlers, and Infants

Active, not recruitingNCT06647407

Sanofi Pasteur, a Sanofi CompanyHealthy Volunteers, Meningococcal Immunization

Start: 2024-11-05End: 2027-05-17Target: 750Updated: 2026-01-20

Phase 2

A Study of a Quadrivalent Meningococcal Tetanus Protein Conjugate Vaccine in Infants and Toddlers

CompletedNCT01049035

Sanofi Pasteur, a Sanofi CompanyMeningitis, Meningococcal Infection

Start: 2009-12-16End: 2012-02-13Updated: 2022-03-28

Baby Vaccine Study (Sched3)

CompletedNCT02482636

University of OxfordInfectious Diseases

Start: 2015-08-31End: 2021-06-30Updated: 2021-09-20

Phase 3

Safety, Tolerability, and Immunogenicity of V419 in Healthy Infants When Given at 2, 4, and 11 to 12 Months (V419-008)

CompletedNCT01480258

MCM Vaccines B.V.Bacterial Infections, Virus Diseases

Start: 2011-11-23End: 2013-10-09Updated: 2019-04-02

Safety of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

CompletedNCT03673462

Sanofi Pasteur, a Sanofi CompanyHealthy Volunteers (Meningococcal Infection)

Start: 2018-09-17End: 2023-03-16Updated: 2023-12-14

Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa

CompletedNCT05794230

Sanofi Pasteur, a Sanofi CompanyHealthy Volunteers, Meningococcal Immunisation

Start: 2023-03-27End: 2025-11-15Updated: 2026-01-21

Co-administration Study of an Investigational Live-Attenuated Respiratory Syncytial Virus Vaccine in Infants and Toddlers

TerminatedNCT06397768

Sanofi Pasteur, a Sanofi CompanyRSV Immunization

Start: 2024-05-13End: 2025-09-18Updated: 2026-02-03

Phase 4

Immunogenicity of Rotavirus Vaccine

CompletedNCT01199874

PATHRotavirus Gastroenteritis

Start: 2011-04-30End: 2013-06-30Updated: 2013-08-30

Zinc and/or Probiotic Supplementation of Rotavirus and Oral Polio Virus Vaccines

CompletedNCT01616693

PATHImmunity to Oral Polio Vaccine, Immunity to Oral Rotavirus Vaccine, Shedding of Oral Rotavirus Vaccine

Start: 2012-07-31End: 2013-07-31Updated: 2018-12-26

The Safety and Immunogenicity Study of Rotavirus Vaccine Simultaneously Vaccinated With MR or MMR Vaccine

Sichuan Center for Disease Control and PreventionRotavirus

Start: 2013-12-31End: 2014-08-31Target: 2800Updated: 2014-06-03

Unknown Phase

Gastroenteritis From Rotavirus Infection in Brazilian Children Less Than 5 Years of Age (Study V260-031).

TerminatedNCT01195844

Merck Sharp & Dohme LLCPediatric Gastroenteritis

Start: 2010-08-31End: 2011-11-30Updated: 2015-03-12

Development of a Live Attenuated Rotavirus Vaccine as a Human Infection Challenge Model

CompletedNCT04123119

Centre for Infectious Disease Research in ZambiaDiarrhoeal Disease

Start: 2019-01-22End: 2019-05-10Updated: 2019-10-14

A Surveillance Study on Timing and Coverage Of Rotavirus and MenB Vaccine Co-administration in Campania Region, Italy

Federico II UniversityMeningococcal Infections, Rotavirus Infections, Vaccination

Start: 2022-05-31End: 2023-04-30Target: 2000Updated: 2022-03-17

Related Papers

P-632. Safety of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW-TT) Administered Concomitantly with Routine Pediatric Vaccines in Healthy Infants and Toddlers

Open Forum Infectious Diseases2025-01-291 citations

Safety and immunogenicity of an investigational quadrivalent meningococcal tetanus toxoid conjugate vaccine (MenACYW-TT) co-administered with routine pediatric vaccines in infants and toddlers: A Phase II study

Vaccine2022-02-075 citations

Immunogenicity of the UK group B meningococcal vaccine (4CMenB) schedule against groups B and C meningococcal strains (Sched3): outcomes of a multicentre, open-label, randomised controlled trial.

2021-01-085 citations

Understanding the reactogenicity of 4CMenB vaccine: Comparison of a novel and conventional method of assessing post-immunisation fever and correlation with pre-release in vitro pyrogen testing.

2020-10-24

Pneumococcal conjugate vaccine 13 delivered as one primary and one booster dose (1 + 1) compared with two primary doses and a booster (2 + 1) in UK infants: a multicentre, parallel group randomised controlled trial.

2017-11-2291 citations

A Phase III randomized, double-blind, clinical trial of an investigational hexavalent vaccine given at 2, 4, and 11-12 months.

2016-06-1828 citations

Impact of Withholding Breastfeeding at the Time of Vaccination on the Immunogenicity of Oral Rotavirus Vaccine—A Randomized Trial

PLoS ONE2015-06-0269 citations

Compliance of mothers following recommendations to breastfeed or withhold breast milk during rotavirus vaccination in North India: a randomized clinical trial.

2014-06-285 citations