RNS System

DEVICE3 trials

Sponsors

NeuroPace

Conditions

Drug Resistant EpilepsyEpilepsyFocal EpilepsyLennox Gastaut SyndromeLennox-Gastaut Syndrome, IntractableNeurostimulator; ComplicationsPartial SeizureSeizures

Phase 2

RNS System LGS Feasibility Study

Active, not recruitingNCT05339126

NeuroPaceEpilepsy, Lennox Gastaut Syndrome, Lennox-Gastaut Syndrome, Intractable +2

Start: 2022-10-04End: 2026-12-31Target: 24Updated: 2026-09-15

Unknown Phase

RNS® System Epilepsy Post-Approval Study

CompletedNCT02403843

NeuroPaceEpilepsy

Start: 2015-06-01End: 2026-01-01Updated: 2026-04-09

RNS System RESPONSE Study

TerminatedNCT04839601

NeuroPaceDrug Resistant Epilepsy, Epilepsy, Focal Epilepsy +2

Start: 2021-10-27End: 2025-05-01Updated: 2025-05-22

Related Papers

Clinical trial barriers in neurostimulation for pediatric drug‐resistant epilepsy

Epileptic Disorders2026-09-10

Circadian modulation of aperiodic background and oscillatory activity as a biomarker of seizure burden in Lennox–Gastaut syndrome

Epilepsia2026-08-28

Postapproval Study for Brain-Responsive Neurostimulation for Drug-Resistant Focal Epilepsy: Three-Year Efficacy and Interim Safety Results.

2026-04-24