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Rituximab IV

DRUG4 trials

Sponsors

Hoffmann-La Roche, The Lymphoma Academic Research Organisation, Centre Hospitalier de PAU

Conditions

Follicular LymphomaLymphoma, Large B-Cell, DiffuseMultiple Sclerosis, Chronic ProgressiveNervous System DiseasesNon-Hodgkin's Lymphoma

Phase 2

Intrathecal Rituximab in Progressive Multiple Sclerosis
CompletedNCT02545959
Centre Hospitalier de PAUMultiple Sclerosis, Chronic Progressive, Nervous System Diseases
Start: 2015-11-30End: 2019-09-02Updated: 2019-10-03
A Study on Pharmacokinetics (PK), Efficacy and Safety of Subcutaneous (SC) Versus Intravenous (IV) Rituximab, in Combination With CHOP (Cyclophosphamide, Doxorubicin, Vincristine, Prednisone) in Previously Untreated Participants With CD20 Positive Diffuse Large B-Cell Lymphoma (DLBCL)
CompletedNCT04660799
Hoffmann-La RocheLymphoma, Large B-Cell, Diffuse
Start: 2021-02-24End: 2022-10-11Updated: 2023-10-12

Phase 3

A Study of Rituximab (MabThera) Subcutaneous (SC) Versus Rituximab (MabThera) Intravenous in Participannts With Follicular Non-Hodgkin's Lymphoma
CompletedNCT01200758
Hoffmann-La RocheNon-Hodgkin's Lymphoma
Start: 2011-02-15End: 2017-10-31Updated: 2018-11-27
Follicular Lymphoma IV/SC Rituximab Therapy (FLIRT)
CompletedNCT02303119
The Lymphoma Academic Research OrganisationFollicular Lymphoma
Start: 2015-02-02End: 2021-06-29Updated: 2023-01-10

Related Papers

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Single-Cell Longitudinal Characterization of FL Heterogeneity and Residual Disease in the Bone Marrow from Low-Tumor Burden FL Enrolled in the Flirt Clinical Trial
Blood2023-11-02
PB2307: PHARMACOKINETICS, EFFICACY AND SAFETY OF SUBCUTANEOUS VERSUS INTRAVENOUS RITUXIMAB COMBINED WITH CHOP IN CHINESE PATIENTS WITH UNTREATED CD20-POSITIVE DIFFUSE LARGE B CELL LYMPHOMA: A RANDOMIZED TRIAL
HemaSphere2023-08-01
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Subcutaneous rituximab induction followed by short rituximab maintenance to improve progression-free survival in patients with low-tumor burden follicular lymphoma: Final results of FLIRT phase III trial, a LYSA study.
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No Early Effect of Intrathecal Rituximab in Progressive Multiple Sclerosis (EFFRITE Clinical Trial)
Multiple Sclerosis International2021-03-0819 citations
Follicular Lymphoma Evaluation Index (<scp>FLEX</scp>): A new clinical prognostic model that is superior to existing risk scores for predicting progression‐free survival and early treatment failure after frontline immunochemotherapy
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2014-02-1090 citations
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