risk-reducing salpingo-oophorectomy (RRSO)

PROCEDURE3 trials

Sponsors

Queen Mary University of London, Kyoto Prefectural University of Medicine, Peking University Third Hospital

Conditions

BRCA MutationsBRCA1/2 mutant carriersHereditary Breast and Ovarian Cancer SyndromePrevention of ovarian cancer Cancer Ovarian cancer

Unknown Phase

Risk-Reducing salpingo-oophorectomy in BRCA1/2 mutant carriers

Active, not recruitingJPRN-UMIN000027723

Kyoto Prefectural University of MedicineBRCA1/2 mutant carriers

Start: 2017-09-01Target: 3Updated: 2026-06-29

Early removal of Fallopian tubes and delayed removal of ovaries in women at high risk of ovarian cancer

Active, not recruitingISRCTN25173360

Queen Mary University of LondonPrevention of ovarian cancer Cancer Ovarian cancer

Start: 2018-07-01Target: 2500Updated: 2025-10-27

Development and Validation of an Ovarian Cancer Risk Prediction Model for Family Members of Ovarian Cancer Probands

RecruitingNCT07039552

Peking University Third HospitalBRCA Mutations, Hereditary Breast and Ovarian Cancer Syndrome

Start: 2016-01-01End: 2035-12-30Target: 10000Updated: 2025-06-26

Related Papers

583 Experiences of women following risk-reducing early-salpingectomy and delayed-oophorectomy and salpingo-oophorectomy on the PROTECTOR trial: a qualitative study

2024-03-01

TUBectomy with delayed oophorectomy as an alternative to risk-reducing salpingo-oophorectomy in high-risk women to assess the safety of prevention: the TUBA-WISP II study protocol.

2023-06-0532 citations

Preventing Ovarian Cancer through early Excision of Tubes and late Ovarian Removal (PROTECTOR): protocol for a prospective non-randomised multi-center trial

International Journal of Gynecological Cancer2020-09-0948 citations