Risk-reducing salpingo-oophorectomy

PROCEDURE3 trials

Sponsors

M.D. Anderson Cancer Center, University Medical Center Nijmegen

Conditions

BRCA1 Gene MutationBRCA2 Gene MutationBRIP1 Gene MutationOvarian CancerOvarian CarcinomaRAD51C Gene MutationRAD51D Gene Mutation

Unknown Phase

Prophylactic Salpingectomy With Delayed Oophorectomy

Active, not recruitingNCT01907789

M.D. Anderson Cancer CenterOvarian Carcinoma

Start: 2013-08-26End: 2030-12-31Target: 80Updated: 2026-04-16

Early Salpingectomy (Tubectomy) With Delayed Oophorectomy in BRCA1/2 Gene Mutation Carriers

Active, not recruitingNCT02321228

University Medical Center NijmegenBRCA1 Gene Mutation, BRCA2 Gene Mutation, Ovarian Cancer

Start: 2015-01-31End: 2035-01-31Target: 510Updated: 2024-12-05

TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention

RecruitingNCT04294927

University Medical Center NijmegenBRCA1 Gene Mutation, BRCA2 Gene Mutation, BRIP1 Gene Mutation +3

Start: 2020-03-01End: 2040-02-17Target: 3000Updated: 2026-04-06

Related Papers

Optimization of Timing for Risk-Reducing Salpingectomy and Oophorectomy

Obstetrics and Gynecology2024-11-073 citations

TUBectomy with delayed oophorectomy as an alternative to risk-reducing salpingo-oophorectomy in high-risk women to assess the safety of prevention: the TUBA-WISP II study protocol.

2023-06-0532 citations

Prophylactic Radical Fimbriectomy with Delayed Oophorectomy in Women with a High Risk of Developing an Ovarian Carcinoma: Results of a Prospective National Pilot Study

Cancers2023-02-1019 citations

Cancer worry among BRCA1/2 pathogenic variant carriers choosing surgery to prevent tubal/ovarian cancer: course over time and associated factors.

2022-01-086 citations

648 TUBectomy with delayed oophorectomy as alternative for risk-reducing salpingo-oophorectomy in high-risk women to assess the safety of prevention

2021-10-01

179 Cancer worry among <i>BRCA1/2</i> pathogenic variant carriers choosing surgery to prevent tubal/ovarian cancer

2021-10-01

Evaluation of a patient decision aid for BRCA1/2 pathogenic variant carriers choosing an ovarian cancer prevention strategy.

2021-08-275 citations

Association of Salpingectomy With Delayed Oophorectomy Versus Salpingo-oophorectomy With Quality of Life in <i>BRCA1/2</i> Pathogenic Variant Carriers

JAMA Oncology2021-06-0366 citations

577 Early salpingectomy (tubectomy) with delayed oophorectomy as an alternative for risk-reducing salpingo-oophorectomy to improve quality of life in women with a BRCA1/2 pathogenic variant (tuba study): a prospective multicenter preference trial

2020-12-011 citations

P1239 Better quality of life in <i>BRCA</i> mutation carriers after salpingectomy with delayed oophorectomy compared to salpingo-oophorectomy; first results of the Dutch TUBA study

2019-11-01

Prophylactic salpingectomy with delayed oophorectomy (PSDO): Feasibility study in women with BRCA mutations.

Journal of Clinical Oncology2016-05-202 citations

Early salpingectomy (TUbectomy) with delayed oophorectomy to improve quality of life as alternative for risk-reducing salpingo-oophorectomy in BRCA1/2 mutation carriers (TUBA study): a prospective non-randomised multicentre study.

2015-08-1983 citations