rilzabrutinib SAR444671

DRUG2 trials

Sponsors

Principia Biopharma, a Sanofi Company, Sanofi Aventis Recherche and Development

Conditions

Haematological DisordersHealthy Volunteers

Phase 1

Food Effect and Relative Bioavailability Study of Rilzabrutinib in Healthy Participants

CompletedNCT04748926

Principia Biopharma, a Sanofi CompanyHealthy Volunteers

Start: 2021-04-07End: 2021-05-21Updated: 2025-09-23

Phase 3

The efficacy and safety of rilzabrutinib in participants aged 10 to 65 years with sickle-cell disease

Active, not recruitingPACTR202505901903077

Sanofi Aventis Recherche and DevelopmentHaematological Disorders

Start: 2026-09-24Target: 192Updated: 2026-09-14