rhTSH

DRUG6 trials

Sponsors

Copenhagen University Hospital at Herlev, University of Colorado, Denver, Gustave Roussy, Cancer Campus, Grand Paris, Suzhou Zelgen Biopharmaceuticals Co.,Ltd, Massachusetts General Hospital

Conditions

Differentiated Thyroid CancerFollicular Thyroid CancerMetastatic Radioactive Iodine Refractory Thyroid Cancer Patients With RAS or BRAF MutationMetastatic Thyroid CancerPapillary Thyroid CancerThyroid CancerThyroid CarcinomaUnresectable Thyroid Gland Carcinoma

Phase 1

Evaluation of Thyroid Stunning From a Diagnostic Dose of I-123

CompletedNCT02278198

University of Colorado, DenverDifferentiated Thyroid Cancer

Start: 2012-11-30End: 2019-09-20Updated: 2019-10-24

Phase 2

Efficacy of MEK (Trametinib) and BRAFV600E (Dabrafenib) Inhibitors With Radioactive Iodine (RAI) for the Treatment of Refractory Metastatic Differentiated Thyroid Cancer

CompletedNCT03244956

Gustave Roussy, Cancer Campus, Grand ParisMetastatic Radioactive Iodine Refractory Thyroid Cancer Patients With RAS or BRAF Mutation

Start: 2017-12-27End: 2026-01-15Updated: 2026-03-23

Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC

RecruitingNCT05668962

Massachusetts General HospitalFollicular Thyroid Cancer, Metastatic Thyroid Cancer, Papillary Thyroid Cancer +3

Start: 2023-03-01End: 2026-01-01Target: 30Updated: 2024-12-12

Phase 3

rhTSH for Radioactive Iodine Remnant Ablation in Participants With Differentiated Thyroid Cancer (DTC)

CompletedNCT04964284

Suzhou Zelgen Biopharmaceuticals Co.,LtdDifferentiated Thyroid Cancer

Start: 2021-10-06End: 2026-01-31Updated: 2026-09-08

Comparison of the Efficacy and Safety of rhTSH as An Adjunctive Diagnostic Tool in Differentiated Thyroid Cancer Patients Who Had Been Thyroidectomized Vs. Patients Who After Thyroid Hormone Withdrawal

CompletedNCT04971473

Suzhou Zelgen Biopharmaceuticals Co.,LtdDifferentiated Thyroid Cancer

Start: 2021-09-10End: 2023-07-05Updated: 2024-03-28

Phase 4

Quality of Life, Recombinant TSH (Thyrogen) and Thyroid Cancer

CompletedNCT00604318

Copenhagen University Hospital at HerlevThyroid Cancer

Start: 2008-02-29End: 2012-02-29Updated: 2013-01-10

Related Papers

RhTSH in aiding dynamic assessment in patients with differentiated thyroid Cancer.

2025-06-09