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Revlimid 20 mg hard capsules

DRUG17 trials

Sponsors

Incyte Corp., AbbVie Deutschland GmbH & Co. KG, Sanofi-Aventis Recherche & Developpement, Janssen - Cilag International, Epizyme Inc.

Conditions

B-cell Non-Hodgkin's lymphomaCancerDiffuse large B-cell lymphoma) and aggressive B-cell lymphomas (HGBCLDiffuse large B-cell lymphomas (DLBCLFollicular LymphomaHigh-grade B-cell lymphoma) originate from mature B-cells at various stages of terminal differentiationMultiple MyelomaMyeloma multiplex

Phase 1

Phase 2

Phase 3

A Phase 3 Study Comparing Daratumumab, VELCADE (bortezomib), Lenalidomide, and Dexamethasone (D-VRd) with VELCADE, Lenalidomide, and Dexamethasone (VRd) in Subjects with Untreated Multiple Myeloma and for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy
CompletedCTIS2023-507312-13-00
Janssen - Cilag InternationalMultiple Myeloma
Start: 2018-11-15End: 2025-10-30Target: 157Updated: 2025-05-05
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Tafasitamab Plus Lenalidomide in Addition to Rituximab Versus Lenalidomide in Addition to Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma Grade 1 to 3a or R/R Marginal Zone Lymphoma
Active, not recruitingCTIS2023-504684-16-00
Incyte Corp.follicular lymphoma (FL) and marginal zone lymphoma (MZL)
Start: 2021-06-05Target: 345Updated: 2025-10-02
A Phase 3 randomized, open-label, multicenter study of isatuximab (SAR650984) in combination with lenalidomide and dexamethasone versus lenalidomide and dexamethasone in patients with high-risk smoldering multiple myeloma
Active, not recruitingCTIS2023-507419-37-00
Sanofi-Aventis Recherche & DeveloppementPlasma cell myeloma
Start: 2020-06-25Target: 272Updated: 2025-10-06
A Phase 3, Open-Label Study to Evaluate Safety and Efficacy of Epcoritamab in Combination with Rituximab and Lenalidomide (R2) compared to R2 in Subjects with Relapsed or Refractory Follicular Lymphoma (EPCORE™ FL-1)
Active, not recruitingCTIS2023-505628-67-00
AbbVie Deutschland GmbH & Co. KGRelapsed and Refractory Follicular Lymphoma
Start: 2022-10-28Target: 280Updated: 2025-12-19
A Phase 3, Multicenter, Randomized, Open-Label Trial to Evaluate the Safety and Efficacy of Epcoritamab + Rituximab and Lenalidomide (R2) compared to Chemoimmunotherapy in Previously Untreated Follicular Lymphoma (EPCORE™FL-2)
Active, not recruitingCTIS2023-506906-38-00
AbbVie Deutschland GmbH & Co. KGFollicular Lymphoma
Start: 2024-05-23Target: 357Updated: 2026-01-20
A Phase 3 Randomized, Open-Label, Multicenter Study Evaluating the Efficacy of Axicabtagene Ciloleucel Versus Standard of Care Therapy in Subjects with Relapsed/Refractory Follicular Lymphoma
Active, not recruitingCTIS2024-511594-30-00
Kite Pharma Inc.Relapsed/Refractory Follicular Lymphoma
Start: 2023-02-23Target: 142Updated: 2026-01-14
SYMPHONY-1: A PHASE 1B/3 DOUBLE-BLIND, RANDOMIZED, ACTIVE-CONTROLLED, 3-STAGE, BIOMARKER ADAPTIVE STUDY OF TAZEMETOSTAT OR PLACEBO IN COMBINATION WITH LENALIDOMIDE PLUS RITUXIMAB IN SUBJECTS WITH RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA
RecruitingCTIS2024-510690-16-00
Epizyme Inc.Relapsed/refractory follicular lymphoma
Start: 2022-01-31Target: 226Updated: 2025-06-26
CARFILZOMIB - LENALIDOMIDE - DEXAMETHASONE (KRd) versus LENALIDOMIDE - DEXAMETHASONE (Rd) IN NEWLY DIAGNOSED MYELOMA PATIENTS NOT ELIGIBLE FOR AUTOLOGOUS STEM CELL TRANSPLANTATION: A RANDOMIZED PHASE III TRIAL (EMN20)
Active, not recruitingCTIS2024-513396-41-00
Fondazione European Myeloma Network Italy O.N.L.U.S.PATIENTS WITH NEW DIAGNOSIS MULTIPLE MYELOMA WITH AGE >= 65 YEARS OR NOT ELIGIBLE TO ASCT
Start: 2019-05-15Target: 340Updated: 2025-12-15
A Phase 3, Multicenter, Randomized, Open-Label Study of Epcoritamab Plus Lenalidomide Compared to Rituximab Plus Gemcitabine and Oxaliplatin in Participants with Relapsed or Refractory Diffuse Large B-Cell Lymphoma
RecruitingCTIS2024-510965-41-00
AbbVie Deutschland GmbH & Co. KGRelapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)
Start: 2024-09-03Target: 116Updated: 2025-12-15
Phase III study of Isatuximab-Carfilzomib-Lenalidomide-Dexamethasone (Isa-KRd) versus Carfilzomib-Lenalidomide-Dexamethasone (KRd) in newly diagnosed multiple myeloma patients eligible for autologous stem cell transplantation (IsKia TRIAL)
RecruitingCTIS2024-513422-38-00
European Myeloma Network B.V., Emn Trial Office S.r.l. Impresa SocialeNewly diagnosed multiple myeloma
Start: 2020-09-28Target: 302Updated: 2025-07-23
A Phase 3 Randomized, Open-label, Multicenter Study Assessing the Clinical Benefit of Isatuximab (SAR650984) in Combination with Bortezomib (Velcade®), Lenalidomide and Dexamethasone versus Bortezomib, Lenalidomide and Dexamethasone in Patients with Newly Diagnosed Multiple Myeloma Not Eligible for Transplant
Active, not recruitingCTIS2024-514417-34-00
Sanofi-Aventis Recherche & DeveloppementCancer
Start: 2017-12-14Target: 308Updated: 2025-05-12
A Randomized, Open-label Phase 3 Study of Carfilzomib, Lenalidomide, and Dexamethasone Versus Bortezomib, Lenalidomide and Dexamethasone (KRd vs. VRd) in Patients With Newly Diagnosed Multiple Myeloma (COBRA)
Active, not recruitingCTIS2024-518473-34-00
Polish Myeloma ConsortiumMultiple Myeloma
Start: 2019-11-20Target: 233Updated: 2025-04-02

Phase 4