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Replens
DEVICE
2 trials
Sponsors
Polly A. Niravath, MD
, Fred Hutchinson Cancer Center
Conditions
Atrophy of Vagina
Breast Cancer
Dyspareunia (Female)
Estrogen Receptor Positive Breast Cancer
Menopause
Phase 2
REVIVE: Replens Versus Intra-Vaginal Estrogen for the Treatment of Vaginal Dryness on Aromatase Inhibitor Therapy
Active, not recruiting
NCT01984138
Polly A. Niravath, MD
Breast Cancer, Estrogen Receptor Positive Breast Cancer
Start: 2013-09-01
End: 2026-06-01
Updated: 2026-01-28
Phase 3
The Vaginal Health Trial
Completed
NCT02516202
Fred Hutchinson Cancer Center
Atrophy of Vagina, Dyspareunia (Female), Menopause
Start: 2016-04-30
End: 2017-07-31
Updated: 2018-07-12
Related Papers
Association of Vaginal Estradiol Tablet With Serum Estrogen Levels in Women Who Are Postmenopausal
JAMA Network Open
2022-11-14
20 citations
Impact of Topical Interventions on the Vaginal Microbiota and Metabolome in Postmenopausal Women
JAMA Network Open
2022-03-30
27 citations
Comparison of the Vaginal Microbiota in Postmenopausal Black and White Women
The Journal of Infectious Diseases
2020-12-19
13 citations
Sexual frequency and pain in a randomized clinical trial of vaginal estradiol tablets, moisturizer, and placebo in postmenopausal women
Menopause The Journal of The North American Menopause Society
2019-04-15
29 citations
Efficacy of Vaginal Estradiol or Vaginal Moisturizer vs Placebo for Treating Postmenopausal Vulvovaginal Symptoms
JAMA Internal Medicine
2018-03-19
176 citations