Renal Autologous Cell Therapy (REACT)

BIOLOGICAL8 trials

Conditions

CAKUTChronic Kidney DiseaseChronic Kidney DiseasesCongenital Anomalies of Kidney and Urinary TractDiabetic Kidney DiseaseType 1 Diabetes MellitusType 2 Diabetes Mellitus

Phase 1

A Study of a Renal Autologous Cell Therapy (REACT) in Patients With Chronic Kidney Disease (CKD) From Congenital Anomalies of the Kidney and Urinary Tract (CAKUT).

CompletedNCT04115345

ProkidneyChronic Kidney Disease, Congenital Anomalies of Kidney and Urinary Tract

Start: 2019-08-13End: 2023-01-31Updated: 2023-12-21

A Study of Participants With Chronic Kidney Disease Previously Treated With REACT

TerminatedNCT05694169

ProkidneyCAKUT, Chronic Kidney Diseases, Diabetic Kidney Disease

Start: 2023-07-11End: 2024-05-13Updated: 2025-02-28

Phase 2

A Study of Renal Autologous Cell Therapy (REACT) in Type 2 Diabetics With Chronic Kidney Disease

CompletedNCT02836574

ProkidneyChronic Kidney Disease, Type 2 Diabetes Mellitus

Start: 2016-09-30End: 2023-12-31Updated: 2025-08-24

A Study of Autologous Renal Autologous Cell Therapy (REACT) in Patients With Diabetic Chronic Kidney Disease

CompletedNCT03270956

ProkidneyChronic Kidney Disease, Type 2 Diabetes Mellitus

Start: 2018-04-25End: 2022-11-17Updated: 2025-03-24

Renal Autologous Cell Therapy (REACT) in Subjects With Type 1 or 2 Diabetes and Chronic Kidney Disease (REGEN-007)

CompletedNCT05018416

ProkidneyChronic Kidney Diseases, Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus

Start: 2021-07-27End: 2025-05-20Updated: 2026-03-13

Phase 3

A Study of Renal Autologous Cell Therapy (REACT) in Participants With Type 2 Diabetes and Chronic Kidney Disease

WithdrawnNCT05286853

ProkidneyChronic Kidney Diseases, Type 2 Diabetes Mellitus

Start: 2024-07-17End: 2024-09-03Updated: 2024-09-25

Unknown Phase

A Long-Term Follow-Up Study of Participants Exposed to REACT

RecruitingNCT05918523

ProkidneyChronic Kidney Diseases, Diabetic Kidney Disease

Start: 2023-12-11End: 2028-03-01Target: 80Updated: 2026-09-01

Long-Term Follow-up Study of Participants Exposed to Renal Autologous Cell Therapy Frozen Product

Enrolling by invitationNCT06790498

ProkidneyChronic Kidney Disease, Diabetic Kidney Disease

Start: 2023-11-23End: 2030-08-31Target: 50Updated: 2026-09-17

Clinical Journal of the American Society of Nephrology2026-01-02

Safety and Feasibility of a Novel Percutaneous Locoregional Injection Technique of Renal Cellular Therapy for Chronic Kidney Disease of Diabetes

Kidney International Reports2021-06-193 citations

Protocol and Baseline Data on Renal Autologous Cell Therapy Injection in Adults with Chronic Kidney Disease Secondary to Congenital Anomalies of the Kidney and Urinary Tract.

2021-03-018 citations