Remimazolam Tosilate

DRUG16 trials

Sponsors

Jiangsu HengRui Medicine Co., Ltd., Fujian Shengdi Pharmaceutical Co., Ltd., RenJi Hospital, Shiyou Wei, Sichuan Provincial People's Hospital

Conditions

Anesthesia InductionAnesthesia for Elective Surgery PatientsCognitionDisease of Respiratory SystemEffect of DrugFrailtyGeneral AnesthesiaLocal Anesthesia Assisted Sedation

Phase 1

A Study of Remimazolam Tosilate for Prolonged Sedation in the ICU

CompletedNCT05913336

Jiangsu HengRui Medicine Co., Ltd.Sedation in the ICU

Start: 2023-06-27End: 2025-03-05Updated: 2025-09-03

Phase 2

A Study Comparing Remimazolam Tosilate and Propofol for Intravenous General Anaesthesia in Operations

CompletedNCT02406872

Jiangsu HengRui Medicine Co., Ltd.General Anesthesia

Start: 2014-12-31End: 2015-08-31Updated: 2015-12-31

A Study of Remimazolam Tosilate in Patients Undergoing Diagnostic Upper GI Endoscopy

CompletedNCT03003884

Jiangsu HengRui Medicine Co., Ltd.Sedation

Start: 2016-11-30End: 2017-03-31Updated: 2017-09-08

A Trial of Efficacy and Safety of Remimazolam Tosilate for Injection in Local Anesthesia Assisted Sedation

CompletedNCT05015361

Jiangsu HengRui Medicine Co., Ltd.Local Anesthesia Assisted Sedation

Start: 2021-05-07End: 2021-07-04Updated: 2021-08-20

A Study of Remimazolam Tosilate for Sedation in the ICU

CompletedNCT05152303

Fujian Shengdi Pharmaceutical Co., Ltd.Sedation in the ICU

Start: 2022-10-12End: 2023-04-19Updated: 2023-05-23

Phase 3

Study of Remimazolam Tosilate in Patients Undergoing Diagnostic Upper GI Endoscopy

CompletedNCT03425474

Jiangsu HengRui Medicine Co., Ltd.Sedation

Start: 2017-09-01End: 2017-11-10Updated: 2018-02-12

Study of Remimazolam Tosilate in Patients Undergoing Colonoscopy

CompletedNCT03779061

Jiangsu HengRui Medicine Co., Ltd.Sedation

Start: 2018-06-28End: 2018-09-28Updated: 2018-12-19

A Clinical Study of Remimazolam Tosilate Compared to Propofol for General Anesthesia During Elective Surgery

CompletedNCT03921775

Jiangsu HengRui Medicine Co., Ltd.Anesthesia for Elective Surgery Patients

Start: 2019-05-13End: 2019-12-30Updated: 2020-05-15

A Clinical Study of Remimazolam Tosilate in Patients Undergoing Bronchoscopy

CompletedNCT04400201

Jiangsu HengRui Medicine Co., Ltd.Sedation

Start: 2020-06-15End: 2020-10-30Updated: 2022-08-22

A Study of Remimazolam Tosilate for Sedation in the ICU

CompletedNCT06222294

Jiangsu HengRui Medicine Co., Ltd.Sedation in the ICU

Start: 2024-03-12End: 2024-09-24Updated: 2026-01-09

Phase 4

Effect on Early Cognition Under Sedation by Rimazole Toluenesulfonate in Old Patient Undergoing Colonoscopy

RecruitingNCT05255211

RenJi HospitalCognition

Start: 2021-12-02End: 2024-12-30Target: 90Updated: 2024-03-18

A Study of Remimazolam Tosilate for Sedation in the Upper Gastrointestinal Endoscopy

CompletedNCT06169995

Jiangsu HengRui Medicine Co., Ltd.Sedation in the Upper Gastrointestinal Endoscopy

Start: 2023-12-11End: 2023-12-16Updated: 2023-12-29

Unknown Phase

95% Effective Dose(ED95) of Remimazolam During Dexmedetomidine Pretreatment

CompletedNCT05631028

Shiyou WeiAnesthesia Induction, Lung Cancer

Start: 2022-12-01End: 2023-01-01Updated: 2023-03-14

Effective Dose of Remimazolam Combined With Propofol in Painless Gastroscopy

CompletedNCT05876793

Sichuan Provincial People's HospitalEffect of Drug

Start: 2023-06-01End: 2023-06-30Updated: 2023-08-01

Application of Low-dose Muscle Relaxants in Bronchoscopic Interventional Procedures

CompletedNCT07035301

Harbin Medical UniversityDisease of Respiratory System

Start: 2025-03-17End: 2025-07-31Updated: 2026-03-03

ED50 of Remimazolam for Anesthesia Induction in Frail Elderly Patients

CompletedNCT07467603

The First Hospital of Hebei Medical UniversityAnesthesia Induction, Frailty

Start: 2025-02-01End: 2025-04-30Updated: 2026-03-12

Related Papers

Efficacy and Safety of Remimazolam Tosylate versus Propofol for Sedation of Postoperative Mechanically Ventilated Patients in Intensive Care Units: a Multicenter, Randomized, Single-blind, Non-inferiority, Phase 3 trial

Anesthesiology2026-03-19

Effect of remimazolam tosilate for injection (HR7056) versus sevoflurane on the incidence of postoperative delirium in older patients undergoing total hip arthroplasty: study protocol for a prospective, multicentre, two-arm, parallel-group, randomised controlled trial.

2025-02-18

Effect of pre-use of Dexmedetomidine on the effective inhibitory dose of remimazolam tosilate on positive cardiovascular response in double-lumen endobronchial intubation: a clinical study.

2023-11-233 citations

Study Protocol of a Multicenter, Randomized, Single-Blind Trial: Efficacy and Safety of Remimazolam Tosylate for Sedation in ICU Patients.

2023-03-152 citations

Efficacy and Safety of Remimazolam Tosilate Combined With Esketamine for Analgesic Sedation in Mechanically Ventilated ICU Patients: A Single-Arm Clinical Study Protocol

Frontiers in Medicine2022-03-1718 citations