Relacorilant
Sponsors
Corcept Therapeutics Inc., Corcept Therapeutics, University of Chicago
Conditions
Adrenocortical CarcinomaAdvancedCushing SyndromeGynecological CancersHealthyHepatic ImpairmentHigh-Grade Epithelial OvarianHypercortisolism
Phase 1
Study in Healthy Subjects to Determine the Effect of Relacorilant on Exposure to Probe Substrates for Cytochrome P450s
CompletedNCT03457597
Start: 2018-03-06End: 2018-04-28Updated: 2018-05-17
Study of Drug 1 (Enzalutamide) Plus Drug 2 (Relacorilant) for Patients With Prostate Cancer
CompletedNCT03674814
Start: 2018-10-23End: 2024-06-10Updated: 2026-03-31
Study of Relacorilant in Combination With Pembrolizumab for Patients With Adrenocortical Carcinoma Which Produces Too Much Stress Hormone (Cortisol)
CompletedNCT04373265
Start: 2020-09-30End: 2024-01-12Updated: 2024-02-23
T/QT Study to Investigate the Effect of Relacorilant on Cardiac Repolarization in Healthy Volunteers
CompletedNCT04795479
Start: 2021-01-22End: 2021-07-13Updated: 2021-09-14
Effect of Relacorilant on the Pharmacokinetics of the Sensitive P-glycoprotein Substrate Dabigatran Etexilate in Healthy Participants
CompletedNCT05347979
Start: 2022-05-25End: 2022-07-19Updated: 2023-02-09
A Study to Evaluate the Effects of Hepatic Impairment on the Pharmacokinetics of Relacorilant
CompletedNCT06094725
Start: 2020-01-06End: 2020-12-14Updated: 2023-10-23
Phase 2
Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome
Active, not recruitingNCT03604198
Start: 2018-05-07End: 2026-12-01Updated: 2026-02-19
Study of Relacorilant in Combination With Nab-Paclitaxel for Patients With Recurrent Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
CompletedNCT03776812
Start: 2019-04-05End: 2023-07-12Updated: 2025-10-07
A Study of Enzalutamide Plus the Glucocorticoid Receptor Antagonist Relacorilant Versus Placebo for Patients With High-risk Localized Prostate Cancer
RecruitingNCT05726292
Start: 2025-01-06End: 2028-04-01Target: 90Updated: 2026-03-04
An Open-label, Global, Multi-Arm Study to Evaluate the Efficacy and Safety of Relacorilant in Combination with Different Treatment Regimens in Patients with Gynecological Cancers (BELLA)
RecruitingCTIS2024-517432-21-00
Start: 2025-05-30Target: 177Updated: 2026-01-27
Phase 3
A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome
CompletedNCT03697109
Start: 2018-11-15End: 2024-04-15Updated: 2025-07-16
A Study of the Efficacy and Safety of Relacorilant in Patients With Cortisol-Secreting Adrenal Adenomas
CompletedNCT04308590
Start: 2020-07-27End: 2024-09-19Updated: 2025-09-04
A Phase 3 Study of Relacorilant in Combination with Nab-Paclitaxel versus Nab-Paclitaxel Monotherapy in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer (ROSELLA)
Active, not recruitingCTIS2024-514080-25-00
Start: 2023-04-21Target: 205Updated: 2025-06-27
Related Papers
1 more papers not shown