Regorafenib (BAY73-4506)
Sponsors
Bayer, National Cancer Institute, Naples
Conditions
Colorectal Cancer MetastaticColorectal NeoplasmsGastrointestinal Stromal TumorsPediatric OncologyTumors
Phase 1
Study to Determine Safety, Pharmacokinetics, Pharmacodynamics of BAY73-4506 in Combination With mFOLFOX6 or FOLFIRI
CompletedNCT00934882
Start: 2009-08-31End: 2012-04-30Updated: 2014-06-02
Phase I Study to Investigate Pharmacokinetics and Safety of BAY73-4506 in Asian (Japanese) Patients With Solid Tumors.
CompletedNCT00960258
Start: 2009-07-01End: 2013-11-11Updated: 2017-09-27
A Phase I Dose Finding Study in Children With Solid Tumors Recurrent or Refractory to Standard Therapy
CompletedNCT02085148
Start: 2014-04-11End: 2024-03-13Updated: 2024-04-22
Phase 2
Phase 3
Unknown Phase
Regorafenib in Subjects With Metastatic Colorectal Cancer (CRC) Who Have Progressed After Standard Therapy
NCT01538680
Updated: 2019-05-29
Regorafenib in Subjects With Gastrointestinal Stromal Tumors (GIST) Who Have Progressed After Standard Therapy
NCT01646593
Updated: 2014-12-15
Regorafenib in Subjects With Gastrointestinal Stromal Tumors (GIST) Who Have Progressed After Standard Therapy (Managed Access Program)
NCT01689376
Updated: 2016-08-16