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REGN9933

DRUG9 trials

Sponsors

Regeneron Pharmaceuticals Inc., Regeneron Pharmaceuticals

Conditions

Atrial Fibrillation (AF)Healthy VolunteersPeripheral Artery Disease (PAD)Thromboembolic diseaseVenous Thromboembolism

Phase 1

Phase 2

A Trial to Learn How Well REGN9933 Works for Preventing Blood Clots After Knee Replacement Surgery in Adult Participants
CompletedNCT05618808
Regeneron PharmaceuticalsVenous Thromboembolism
Start: 2023-05-24End: 2024-05-27Updated: 2025-08-29
A Phase 2, Multicenter, Randomized, Open-Label, Active-Control Study of REGN9933, a Factor XI Monoclonal Antibody, for Prevention of Venous Thromboembolism after Elective, Unilateral, Total Knee Arthroplasty
CompletedCTIS2022-501470-18-00
Regeneron Pharmaceuticals Inc.Thromboembolic disease
Start: 2023-06-26End: 2024-05-27Target: 408Updated: 2024-04-15
A Trial to Learn How Well REGN9933 and REGN7508 Work for Preventing Blood Clots, and How Safe They Are, in Adults Who Have a Peripherally Inserted Central Catheter (PICC)
Active, not recruitingNCT06299111
Regeneron PharmaceuticalsVenous Thromboembolism
Start: 2024-09-20End: 2026-06-01Updated: 2026-01-12
A Master Protocol for a Phase 2 Randomized, Double-blind, Placebo-controlled Study of REGN9933 and REGN7508, Monoclonal Antibodies against Factor XI for Prevention of Venous Thromboembolism in Patients with a Peripherally Inserted Central Catheter (ROXI-CATH).
RecruitingCTIS2023-508603-21-00
Regeneron Pharmaceuticals Inc.Venous Thromboembolism
Start: 2024-09-20Target: 93Updated: 2026-01-26
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
RecruitingNCT07175428
Regeneron PharmaceuticalsAtrial Fibrillation (AF)
Start: 2025-10-20End: 2027-04-21Target: 1200Updated: 2026-03-18

Phase 3

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