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REGN9933

DRUG13 trials

Sponsors

Regeneron Pharmaceuticals Inc., Regeneron Pharmaceuticals

Conditions

Atrial Fibrillation (AF)End-Stage Kidney Disease (ESKD)Healthy VolunteersPeripheral Artery DiseasePeripheral Artery Disease (PAD)Thromboembolic diseaseVenous ThromboembolismVenous Thromboembolism (VTE)

Phase 1

Phase 2

Phase 3

Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease
RecruitingNCT07318610
Regeneron PharmaceuticalsPeripheral Artery Disease (PAD)
Start: 2026-07-10End: 2029-11-16Target: 7050Updated: 2026-10-22
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
RecruitingNCT07430956
Regeneron PharmaceuticalsAtrial Fibrillation (AF)
Start: 2026-04-03End: 2029-06-26Target: 2628Updated: 2026-10-14
Venous Thromboembolism (VTE) Prophylaxis With REGN7508 and REGN9933 in Adult and Adolescent Participants With a Peripherally Inserted Central Catheter (PICC)
RecruitingNCT07697599
Regeneron PharmaceuticalsVenous Thromboembolism (VTE)
Start: 2026-09-07End: 2029-09-18Target: 1908Updated: 2026-09-29
A Master Protocol for a Phase 3, Multicenter, Randomized Study to Evaluate the Efficacy and Safety of REGN7508 and REGN9933, Monoclonal Antibodies Against Factor XI, in Participants with Recent Lower Extremity Revascularization for Symptomatic Peripheral Artery Disease (ROXI-PALISADE)
Not yet recruitingCTIS2025-522954-37-00
Regeneron Pharmaceuticals Inc.Peripheral Artery Disease
Target: 1215Updated: 2026-09-30
A Master Protocol for a Phase 3, Randomized, Multicenter, Double-blind Study to Assess Stroke and Systemic Embolism Prevention with REGN7508 and REGN9933, Monoclonal Antibodies Against Factor XI, versus Placebo in Participants with Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable (ROXI-INCLINE)
Not yet recruitingCTIS2025-521618-25-00
Regeneron Pharmaceuticals Inc.Atrial Fibrillation (AF)
Target: 237Updated: 2026-09-30

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