recombinant tissue plasminogen activator

DRUG9 trials

Conditions

Acute Pulmonary EmbolismCerebrovascular StrokeEmbolismIschemic StrokeLarge-Artery Atherosclerosis (Embolus/Thrombosis)Massive Pulmonary EmbolismPulmonary EmbolismPulmonary Embolism and Thrombosis

Phase 1

Treatment for Blood Clots in the Veins of the Legs

CompletedNCT00001713

National Institutes of Health Clinical Center (CC)Embolism, Thrombophlebitis

Start: 1998-02-28End: 2006-01-31Target: 20Updated: 2008-03-04

In Vivo Angiostatin Generation Using Tissue Plasminogen Activator and Captopril in Treating Patients With Progressive Metastatic Cancer

CompletedNCT00086723

Northwestern UniversityUnspecified Adult Solid Tumor, Protocol Specific

Start: 2003-07-31End: 2006-01-31Updated: 2012-06-11

Phase 2

Interventional Management of Stroke (IMS) II Study

CompletedNCT00243906

University of CincinnatiStroke

Start: 2003-01-31End: 2007-05-31Updated: 2012-07-25

Safety and Efficacy of the Penumbra™ System in Acute Middle Cerebral Artery (MCA) Stroke

WithdrawnNCT01133223

Hospital de Clinicas de Porto AlegreStroke

Start: 2010-05-31End: 2015-09-30Updated: 2015-09-03

Sonothrombolysis Potentiated by Microbubbles for Acute Ischemic Stroke

CompletedNCT01678495

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauCerebrovascular Stroke

Start: 2012-08-31End: 2015-07-31Updated: 2015-08-10

Phase 3

Submassive and Massive Pulmonary Embolism Treatment With Ultrasound Accelerated Thrombolysis Therapy

CompletedNCT01513759

Boston Scientific CorporationAcute Pulmonary Embolism, Massive Pulmonary Embolism, Pulmonary Embolism +2

Start: 2012-06-07End: 2013-02-17Updated: 2021-07-19

Thrombolysis Endovascular Treatment of Pulmonary Embolism

CompletedNCT03966079

Beijing Tsinghua Chang Gung HospitalAcute Pulmonary Embolism, Pulmonary Embolism

Start: 2017-01-01End: 2020-01-31Updated: 2020-11-30

Phase 4

Optimum Duration of Acoustic Pulse Thrombolysis Procedure in Acute Pulmonary Embolism

CompletedNCT02396758

Boston Scientific CorporationPulmonary Embolism and Thrombosis

Start: 2015-06-12End: 2020-01-30Updated: 2021-07-19

Direct Mechanical Thrombectomy Versus Bridging Therapy

CompletedNCT05155540

Alexandria UniversityIschemic Stroke, Large-Artery Atherosclerosis (Embolus/Thrombosis), Thrombectomy

Start: 2019-07-01End: 2020-09-01Updated: 2022-01-03

Circulation Cardiovascular Interventions2020-08-0133 citations

Risk factors for major bleeding in the SEATTLE II trial

Vascular Medicine2016-12-0336 citations

A Prospective, Single-Arm, Multicenter Trial of Ultrasound-Facilitated, Catheter-Directed, Low-Dose Fibrinolysis for Acute Massive and Submassive Pulmonary Embolism: The SEATTLE II Study.

2015-08-01614 citations