FindTrial
Sign In

Rapamune

DRUG8 trials

Sponsors

Wyeth is now a wholly owned subsidiary of Pfizer, The Cleveland Clinic, Yale University, Le Bonheur Children's Hospital, The University of Texas Health Science Center at San Antonio

Conditions

Advanced Solid CancersAlzheimer DiseaseChronic Kidney FailureCognitive Impairment, MildFacial AngiofibromaGraft vs Host DiseaseHeart FailureKidney Failure

Early Phase 1

Cognition, Age, and RaPamycin Effectiveness - DownregulatIon of thE mTor Pathway
CompletedNCT04200911
The University of Texas Health Science Center at San AntonioAlzheimer Disease, Cognitive Impairment, Mild
Start: 2020-06-01End: 2022-01-13Updated: 2025-01-08

Phase 1

Pilot Study of Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD)
CompletedNCT00286156
The Cleveland ClinicPolycystic Kidney Diseases
Start: 2006-10-31End: 2014-12-31Updated: 2015-04-06
A Study of the mTOR Inhibitor Rapamycin (Rapamune, Sirolimus) in Combination With Abraxane in Advanced Solid Cancers
TerminatedNCT00337376
Yale UniversityAdvanced Solid Cancers
Start: 2006-02-28End: 2010-07-31Updated: 2014-01-14
Tuberous Sclerosis Complex: Facial Angiofibroma Skin Cream
CompletedNCT01853423
Le Bonheur Children's HospitalFacial Angiofibroma
Start: 2013-10-31End: 2016-07-31Updated: 2016-08-19
Effect of Rapamycin to Improve Cardiac Function in Frail Older Adults
CompletedNCT04996719
Mayo ClinicHeart Failure
Start: 2022-05-24End: 2023-08-25Updated: 2023-09-28

Phase 3

Study Comparing Sirolimus/Prograf vs Sirolimus/CsA in High-Risk Renal Transplant Recipients
CompletedNCT00470665
Wyeth is now a wholly owned subsidiary of PfizerRenal Allograft Recipients
Start: 2002-08-31End: 2004-07-31Target: 460Updated: 2007-05-08

Phase 4

Study Evaluating Sirolimus in End Stage Renal Disease in High Risk Kidney Transplant Recipients
CompletedNCT00044720
Wyeth is now a wholly owned subsidiary of PfizerChronic Kidney Failure, Graft vs Host Disease, Kidney Transplantation
End: 2005-07-31Updated: 2009-08-18
Study Evaluating Sirolimus in Kidney Transplant Recipients in India
CompletedNCT00195481
Wyeth is now a wholly owned subsidiary of PfizerGraft vs Host Disease, Kidney Failure
Start: 2004-04-30End: 2005-12-31Target: 100Updated: 2007-12-28

Related Papers

Rapamycin treatment for Alzheimer's disease and related dementias: a pilot phase 1 clinical trial.
2025-05-204 citations