Radiation Therapy (RT)

RADIATION14 trials

Conditions

Breast CancerCancer of the EsophagusGBMHead and Neck CancerHead and Neck Squamous Cell CarcinomaHigh Grade GliomaLeukemiaLymphoma

Phase 1

Doxorubicin Plus External-Beam Radiation Therapy in Treating Patients With Soft Tissue Sarcoma

CompletedNCT00004109

M.D. Anderson Cancer CenterSarcoma

Start: 1998-03-31End: 2011-04-30Updated: 2012-08-02

Radiation Therapy Plus Doxorubicin in Treating Patients With Resectable Primary or Recurrent Retroperitoneal Soft Tissue Sarcoma

CompletedNCT00004123

M.D. Anderson Cancer CenterSarcoma

Start: 1997-07-31End: 2009-10-31Updated: 2012-07-30

Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

CompletedNCT00005092

M.D. Anderson Cancer CenterLeukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm +1

Start: 1999-05-28End: 2002-08-28Updated: 2018-10-26

Radiation Therapy Plus Fludarabine in Treating Patients With Locally Advanced Cancer of the Mouth, Pharynx, or Larynx

CompletedNCT00004246

M.D. Anderson Cancer CenterHead and Neck Cancer

Start: 1995-06-07End: 2002-12-02Updated: 2018-10-25

Phase I/II Study of Panitumumab, Capecitabine and Oxaliplatin w EBRT for Esophageal Cancer

CompletedNCT00578071

Brian CzitoCancer of the Esophagus

Start: 2007-12-31End: 2012-06-30Updated: 2015-07-02

Sunitinib Malate, Hormone Ablation and Radiation Therapy in Patients With Prostate Cancer

CompletedNCT00631527

M.D. Anderson Cancer CenterProstate Cancer

Start: 2008-02-29Updated: 2015-01-29

Locally Advanced Breast Cancer: Individualized Treatment Based On Tumor Molecular Characteristics

TerminatedNCT02297230

NYU Langone HealthBreast Cancer

Start: 2002-06-30End: 2014-12-02Updated: 2018-10-15

Radiation Therapy and MK-3475 for Patients With Recurrent/Metastatic Head and Neck Cancer, Renal Cell Cancer, Melanoma, and Lung Cancer

CompletedNCT02318771

Sidney Kimmel Cancer Center at Thomas Jefferson UniversityHead and Neck Squamous Cell Carcinoma, Metastatic Renal Cell Cancer, Recurrent Head and Neck Carcinoma +6

Start: 2015-02-05End: 2021-03-25Updated: 2025-05-15

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

RecruitingNCT06504381

University of California, San FranciscoHigh Grade Glioma, MGMT-Methylated Glioblastoma, MGMT-Unmethylated Glioblastoma

Start: 2025-01-08End: 2042-01-31Target: 70Updated: 2026-03-11

Phase 2

Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastoma

CompletedNCT03367715

NYU Langone HealthGBM, MGMT-unmethylated Glioblastoma (GBM)

Start: 2018-02-07End: 2022-03-17Updated: 2022-07-01

Phase 3

Cisplatin and Etoposide Plus Radiation Followed By Nivolumab/Placebo For Locally Advanced NSCLC

TerminatedNCT02768558

RTOG Foundation, Inc.Non-Small Cell Lung Cancer

Start: 2016-10-17End: 2019-01-23Updated: 2021-06-02

Unknown Phase

A Prospective Trial to Compare Deep Inspiratory Breath Hold (DIBH) With Prone Breast Irradiation

CompletedNCT03437161

NYU Langone HealthBreast Cancer

Start: 2017-01-17End: 2023-02-15Updated: 2023-02-17

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers

RecruitingNCT04221893

University of California, San FranciscoMetastatic Anal Canal Carcinoma, Metastatic Colorectal Carcinoma, Metastatic Esophageal Carcinoma +41

Start: 2020-08-07End: 2028-04-30Target: 28Updated: 2025-10-06

Preoperative Irradiation for Stage I Breast Cancer

RecruitingNCT05464667

Parul BarryBreast Cancer

Start: 2023-07-07End: 2028-03-31Target: 21Updated: 2025-12-12

Journal of Clinical Oncology2023-01-24

Immune Checkpoints are Important Therapeutic Targets in Cancer Immunotherapy

Cancer Science & Research2021-12-30

Treatment of stage III non-small cell lung cancer in the era of immunotherapy: pathological complete response to neoadjuvant pembrolizumab and chemotherapy.

2020-10-0112 citations

Blockade of Tumor-Expressed PD-1 promotes lung cancer growth

OncoImmunology2017-11-28135 citations

Randomized phase III trial of concurrent chemoradiation followed by nivolumab or placebo for locally advanced non-small cell lung cancer (NSCLC) (RTOG 3505).

Journal of Clinical Oncology2017-05-209 citations

An exploratory study to investigate the immunomodulatory activity of radiation therapy in combination with pembrolizumab in patients with renal cell cancer.

Journal of Clinical Oncology2017-05-202 citations

An exploratory study to investigate the immunomodulatory activity of radiation therapy in combination with pembrolizumab in patients with renal cell cancer.

Journal of Clinical Oncology2017-02-205 citations

Treatment Design and Rationale for a Randomized Trial of Cisplatin and Etoposide Plus Thoracic Radiotherapy Followed by Nivolumab or Placebo for Locally Advanced Non-Small-Cell Lung Cancer (RTOG 3505).

2016-10-2649 citations

Immune biomarkers of treatment failure for a patient on a phase I clinical trial of pembrolizumab plus radiotherapy

Journal of Hematology & Oncology2016-09-2227 citations