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RAD001 (Everolimus)

DRUG7 trials

Sponsors

Daniel George, MD, Ahmad Tarhini, National Health Research Institutes, Taiwan, M.D. Anderson Cancer Center, University of Alabama at Birmingham

Conditions

Anaplastic Large Cell Lymphoma, ALK-negativeAngioimmunoblastic T Cell LymphomaCutaneous T Cell LymphomaEndometrial CancerGliomaHepatocellular CarcinomaKidney CancerPeripheral T Cell Lymphoma Unspecified

Phase 1

Vatalanib and Everolimus in Treating Patients With Advanced Solid Tumors
CompletedNCT00303732
Daniel George, MDKidney Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Start: 2004-12-31End: 2012-08-31Updated: 2016-03-03
Randomized Phase I/II of RAD001 in Advanced Hepatocellular Carcinoma (HCC)
NCT00390195
National Health Research Institutes, TaiwanHepatocellular Carcinoma
Start: 2006-10-31End: 2011-06-30Target: 134Updated: 2009-07-02
RAD001 Combined With CHOP in Newly Diagnosed Peripheral T-cell Lymphomas
CompletedNCT01198665
Samsung Medical CenterAnaplastic Large Cell Lymphoma, ALK-negative, Angioimmunoblastic T Cell Lymphoma, Cutaneous T Cell Lymphoma +1
Start: 2010-07-31End: 2014-12-31Updated: 2015-03-03

Phase 2

Phase II Trial of RAD001 (Everolimus) in Previously Treated Small Cell Lung Cancer
CompletedNCT00374140
Ahmad TarhiniSmall Cell Lung Cancer
Start: 2006-10-31End: 2012-06-30Updated: 2017-10-19
Everolimus (RAD001) as Therapy for Patients With Systemic Mastocytosis
CompletedNCT00449748
M.D. Anderson Cancer CenterSystemic Mastocytosis
Start: 2007-04-01End: 2009-10-01Updated: 2026-07-06
Letrozole and RAD001 With Advanced or Recurrent Endometrial Cancer
Active, not recruitingNCT01068249
M.D. Anderson Cancer CenterEndometrial Cancer
Start: 2010-04-30End: 2028-04-30Updated: 2026-04-30
Everolimus for Children With NF1 Chemotherapy-Refractory Radiographic Progressive Low Grade Gliomas
CompletedNCT01158651
University of Alabama at BirminghamGlioma
Start: 2010-07-10End: 2017-10-26Updated: 2020-02-05

Related Papers

Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway
Oncotarget2014-03-1447 citations
Randomised clinical trial: comparison of two everolimus dosing schedules in patients with advanced hepatocellular carcinoma.
2012-11-0857 citations