Pyronaridine-artesunate

DRUG6 trials

Sponsors

Medicines for Malaria Venture, University of Oxford, Royal Tropical Institute, Shin Poong Pharmaceutical Co. Ltd.

Conditions

COVID-19MalariaMalaria, FalciparumUncomplicated Plasmodium Falciparum Malaria

Phase 1

Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunate

CompletedNCT01523002

Medicines for Malaria VentureMalaria

Start: 2012-01-31End: 2012-10-31Updated: 2023-12-14

Phase 2

Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum Malaria

CompletedNCT00331136

Medicines for Malaria VentureUncomplicated Plasmodium Falciparum Malaria

Start: 2006-06-30End: 2006-12-31Updated: 2022-05-05

Efficacy and Safety of Pyronaridine-artesunate for the Treatment in Uncomplicated Falciparum Malaria

CompletedNCT02389439

University of OxfordMalaria, Falciparum

Start: 2015-03-01End: 2016-06-01Updated: 2018-09-20

The Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients

CompletedNCT04475107

Shin Poong Pharmaceutical Co. Ltd.COVID-19

Start: 2020-07-09End: 2021-04-15Updated: 2021-06-01

Four Different Experimental Drug Regimens to Standard of Care for the Treatment of Symptomatic Outpatients With COVID-19

CompletedNCT04532931

Shin Poong Pharmaceutical Co. Ltd.COVID-19

Start: 2020-09-03End: 2021-08-23Updated: 2025-07-28

Phase 3

Pyronaridine-artesunate and Artemether-lumefantrine for the Treatment of Paediatric Malaria

CompletedNCT02411994

Royal Tropical InstituteMalaria

Start: 2015-10-31End: 2017-08-31Updated: 2017-11-27

Related Papers

Safety and efficacy of pyronaridine-artesunate paediatric granules in the treatment of uncomplicated malaria in children: insights from randomized clinical trials and a real-world study.

2024-02-281 citations

Favipiravir and/or nitazoxanide: a randomized, double-blind, placebo-controlled trial of early therapy in COVID-19 in health workers, their household members, and patients treated at IMSS (FANTAZE)

Trials2022-07-227 citations

Plasmodium falciparum gametocyte dynamics after pyronaridine-artesunate or artemether-lumefantrine treatment.

2018-06-0413 citations

Pyronaridine-artesunate and artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children: a randomized controlled non-inferiority trial.

2018-05-1523 citations

Efficacy and Safety of Pyronaridine-Artesunate for Treatment of Uncomplicated Plasmodium falciparum Malaria in Western Cambodia

Antimicrobial Agents and Chemotherapy2016-02-2952 citations

Population Pharmacokinetics of Pyronaridine in Pediatric Malaria Patients

Antimicrobial Agents and Chemotherapy2015-12-1536 citations

Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials.

2013-02-2158 citations