FindTrial
Sign In

pyronaridine artesunate

DRUG7 trials

Sponsors

Medicines for Malaria Venture, Shin Poong Pharmaceutical Co. Ltd., LSTM Liverpool School of Tropical Medicine, University of Sciences Techniques and Technologies of Bamako, Liverpool School of Tropical Medicine

Conditions

MalariaMalaria COVID-19Malaria,Falciparum

Phase 3

Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria Patients
CompletedNCT00422084
Medicines for Malaria VentureMalaria
Start: 2007-01-31End: 2008-05-31Updated: 2021-11-02
Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria
CompletedNCT00440999
Medicines for Malaria VentureMalaria
Start: 2007-03-31End: 2008-09-30Updated: 2021-11-02
Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric Patients
CompletedNCT00541385
Medicines for Malaria VentureMalaria
Start: 2007-10-31End: 2008-11-30Updated: 2021-11-22
Malaria as a risk factor for COVID-19 in western Kenya and Burkina Faso
Active, not recruitingPACTR202009642148520
LSTM Liverpool School of Tropical MedicineMalaria COVID-19
Start: 2020-11-01Target: 142Updated: 2026-01-27
EFFICACY AND SAFETY OF PYRONARIDINE-ARTESUNATE (PYRAMAX) FOR THE TREATMENT OF FALCIPARUM MALARIA IN AFRICAN PREGNANT WOMEN
Active, not recruitingPACTR202011812241529
University of Sciences Techniques and Technologies of BamakoMalaria
Start: 2020-07-01Target: 2002Updated: 2026-01-27
SAFIRE: Safety of Antimalarials in the FIRst Trimester
RecruitingPACTR202505891635396
Liverpool School of Tropical MedicineMalaria
Start: 2025-05-16Target: 1510Updated: 2026-01-27

Phase 4

Cohort Event Monitoring Study of Pyramax®
CompletedNCT03201770
Shin Poong Pharmaceutical Co. Ltd.Malaria,Falciparum
Start: 2017-06-22End: 2019-04-10Updated: 2019-06-26

Related Papers

Development and validation of an ultra-performance liquid chromatography-tandem mass spectrometry method for the quantification of the antimalarial drug pyronaridine in human whole blood.
2024-04-162 citations
Safety and efficacy of pyronaridine-artesunate paediatric granules in the treatment of uncomplicated malaria in children: insights from randomized clinical trials and a real-world study.
2024-02-281 citations
Efficacy and safety of pyronaridine-artesunate (PYRAMAX) for the treatment of <i>P. falciparum</i> uncomplicated malaria in African pregnant women (PYRAPREG): study protocol for a phase 3, non-inferiority, randomised open-label clinical trial
BMJ Open2023-10-0110 citations
Comparison of intermittent screening (using ultra-sensitive malaria rapid diagnostic test) and treatment (using a newly registered antimalarial pyronaridine-artesunate-PYRAMAX®) to standard intermittent preventive treatment with sulfadoxine-pyrimethamine for the prevention of malaria in pregnant women living in endemic areas: ULTRAPYRAPREG.
2022-11-288 citations
Effectiveness of antimalarial drug combinations in treating concomitant urogenital schistosomiasis in malaria patients in Lambaréné, Gabon: A non-randomised event-monitoring study
PLoS neglected tropical diseases2022-10-319 citations
Phase 3 Evaluation of an Innovative Simple Molecular Test for the Diagnosis of Malaria and Follow-Up of Treatment Efficacy in Pregnant Women in Sub-Saharan Africa (Preg-Diagmal)
Tropical Medicine and Infectious Disease2022-09-01
Evidence for in vitro and in vivo activity of the antimalarial pyronaridine against Schistosoma
PLoS neglected tropical diseases2021-06-249 citations
Pyronaridine–artesunate real-world safety, tolerability, and effectiveness in malaria patients in 5 African countries: A single-arm, open-label, cohort event monitoring study
PLoS Medicine2021-06-1546 citations
Population Pharmacokinetics of Pyronaridine in Pediatric Malaria Patients
Antimicrobial Agents and Chemotherapy2015-12-1536 citations
Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials.
2013-02-2158 citations
Pyronaridine-artesunate granules versus artemether-lumefantrine crushed tablets in children with Plasmodium falciparum malaria: a randomized controlled trial.
2012-10-3139 citations
Pyronaridine-artesunate versus chloroquine in patients with acute Plasmodium vivax malaria: a randomized, double-blind, non-inferiority trial.
2011-01-1868 citations
Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial.
2010-04-0196 citations