Pyronaridine

DRUG2 trials

Sponsors

Medicines for Malaria Venture, Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

Conditions

MalariaMalaria InfectionMalaria RecrudescenceMalaria,FalciparumParasitemiaParasitic DiseaseProtozoan Infections

Phase 1

Pyronaridine in Healthy Adult Participants Infected With Blood Stage Malaria

CompletedNCT05287893

Medicines for Malaria VentureMalaria, Malaria,Falciparum, Malaria Recrudescence +3

Start: 2022-04-04End: 2022-09-26Updated: 2025-04-16

Phase 2

Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2)

CompletedNCT05974267

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, GermanyMalaria Infection

Start: 2023-11-28End: 2024-12-29Updated: 2026-02-06