Pyridoxine hydrochloride

DRUG14 trials

Sponsors

Oslo University Hospital HF, National Institute of Allergy and Infectious Diseases (NIAID), Case Comprehensive Cancer Center, Alliance for Clinical Trials in Oncology, National Cancer Centre, Singapore

Conditions

Autism Spectrum DisordersBreast CancerChild MalnutritionColorectal CancerComorbidities and Coexisting ConditionsDermatologic ComplicationsDrug/Agent Toxicity by Tissue/OrganEndometrial Cancer

Phase 1

A Pilot Study of Methodology to Rapidly Evaluate Drugs for Bactericidal Activity, Tolerance, and Pharmacokinetics in the Treatment of Pulmonary Tuberculosis Using Isoniazid and Levofloxacin

CompletedNCT00000778

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Tuberculosis

Target: 44Updated: 2008-08-08

Phase 2

Pyridoxine in primary sclerosing cholangitis

RecruitingCTIS2023-505155-47-00

Oslo University Hospital HFPrimary sclerosing cholangitis

Start: 2024-06-19Target: 26Updated: 2023-11-16

Phase 3

The Treatment of Tuberculosis in HIV-Infected Patients

CompletedNCT00001033

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Tuberculosis

End: 1997-07-31Target: 650Updated: 2021-11-04

Pyridoxine in Preventing Hand-Foot Syndrome in Patients Who Are Receiving Liposomal Doxorubicin for Cancer

CompletedNCT00245050

Case Comprehensive Cancer CenterBreast Cancer, Drug/Agent Toxicity by Tissue/Organ, Endometrial Cancer +3

Start: 2004-04-30End: 2011-09-30Updated: 2011-12-30

Pyridoxine and Topical Urea/Lactic Acid-Based Cream in Preventing Hand-Foot Syndrome in Patients Receiving Capecitabine for Breast Cancer or Other Cancer

CompletedNCT00296036

Alliance for Clinical Trials in OncologyBreast Cancer, Drug/Agent Toxicity by Tissue/Organ, Unspecified Adult Solid Tumor, Protocol Specific

Start: 2006-06-30Updated: 2017-03-16

Pyridoxine in Preventing Hand-Foot Syndrome Caused by Capecitabine in Patients With Cancer

TerminatedNCT00486213

National Cancer Centre, SingaporeDermatologic Complications, Palmar-plantar Erythrodysesthesia, Unspecified Adult Solid Tumor, Protocol Specific

Start: 2007-06-30End: 2014-08-31Updated: 2015-09-24

Pyridoxine in Preventing Hand-Foot Syndrome in Patients Who Are Receiving Capecitabine for Advanced Colorectal Cancer or Breast Cancer

Cambridge University Hospitals NHS Foundation TrustBreast Cancer, Colorectal Cancer, Palmar-plantar Erythrodysesthesia

Start: 2004-12-31Target: 270Updated: 2013-08-02

An Adaptive Multi-arm Trial to Improve Clinical Outcomes Among Children Recovering From Complicated SAM

Active, not recruitingNCT05994742

Queen Mary University of LondonChild Malnutrition, Comorbidities and Coexisting Conditions, HIV +1

Start: 2024-07-15End: 2026-08-15Updated: 2026-03-19

Unknown Phase

Metabolism of Antituberculosis Drugs in HIV-Infected Persons With Tuberculosis

CompletedNCT00000950

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Tuberculosis

Target: 50Updated: 2011-03-02

Preventive Treatment Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous Infection

CompletedNCT00000638

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Tuberculosis

End: 1999-09-30Target: 2000Updated: 2021-11-02

A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in HIV-Infected Patients.

CompletedNCT00000796

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Tuberculosis

End: 1998-10-31Target: 525Updated: 2021-11-03

Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous Infection

CompletedNCT00000636

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Tuberculosis

End: 1997-10-31Target: 2000Updated: 2021-11-02

Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Suspected Latent Tuberculous Infection

CompletedNCT00000959

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Tuberculosis

End: 1996-06-30Target: 600Updated: 2021-11-04

Early Nutritional Intervention in Patients With Autism Spectrum Disorders

CompletedNCT01230359

Hamad Medical CorporationAutism Spectrum Disorders, Stable Clinical Condition in the Last 3 Months

Start: 2010-04-30End: 2011-07-31Updated: 2011-07-19

Related Papers

An adaptive multiarm randomised trial of biomedical and psychosocial interventions to improve convalescence following severe acute malnutrition in sub-Saharan Africa: Co-SAM trial protocol

BMJ Open2025-05-011 citations

Predictors of Hand-Foot Syndrome and Pyridoxine for Prevention of Capecitabine–Induced Hand-Foot Syndrome

JAMA Oncology2017-07-1794 citations

Predictors of hand-foot syndrome (HFS) in randomised double-blind, placebo-controlled trial of pyridoxine for prevention of capecitabine induced HFS.

Journal of Clinical Oncology2015-05-202 citations