Pulmozyme

DRUG5 trials

Sponsors

University of Jena, Northwestern University, University Hospital, Tours, Boston Children's Hospital, Acibadem University

Conditions

COVIDCOVID-19Chronic RhinosinusitisCystic FibrosisHead and Neck Cancer

Early Phase 1

Pilot Study of Pulmozyme (rhDNase) in Patients With Head and Neck Cancers Treated With Radiation Therapy + Chemotherapy

Northwestern UniversityHead and Neck Cancer

Start: 2008-02-29End: 2016-12-31Target: 36Updated: 2013-06-27

Phase 2

Pulmozyme to Improve COVID-19 ARDS Outcomes

Boston Children's HospitalCOVID

Start: 2020-07-05End: 2021-12-31Target: 60Updated: 2021-12-17

Dornase Alpha for the Treatment of COVID-19

Acibadem UniversityCOVID-19

Start: 2020-05-25End: 2020-09-25Target: 60Updated: 2020-06-16

Phase 3

Nasal Inhalation of Dornase Alfa (Pulmozyme) in Patients With Cystic Fibrosis and Chronic Rhinosinusitis

CompletedNCT00265434

University of JenaChronic Rhinosinusitis, Cystic Fibrosis

Start: 2005-12-31End: 2006-05-31Updated: 2014-12-04

Phase 4

RhDNase and Biodistribution of PMN Serine Proteases in Cystic Fibrosis Sputum

CompletedNCT00843817

University Hospital, ToursCystic Fibrosis

Start: 2009-04-30End: 2013-04-30Updated: 2022-03-16