Psilocybin-assisted Psychotherapy

DRUG4 trials

Sponsors

University of Otago, University of British Columbia, Gustavo Vazquez, ARQ National Psychotrauma Centre

Conditions

Chronic PainDemoralizationDepressive Disorder, Treatment-ResistantOpioid DependencePosttraumatic Stress Disorder (PTSD)Safety

Phase 1

Safety and Efficacy of Psilocybin-assisted Psychotherapy for Demoralization Syndrome in Patients Diagnosed With Advanced Stage Cancer

RecruitingNCT06818994

Gustavo VazquezDemoralization, Safety

Start: 2026-04-01End: 2027-06-01Target: 15Updated: 2026-03-18

Phase 2

Standardized Natural Psilocybin-assisted Psychotherapy for Tapering of Opioid Medication

RecruitingNCT05585229

University of British ColumbiaChronic Pain, Opioid Dependence

Start: 2025-10-27End: 2026-08-31Target: 10Updated: 2025-12-04

Psilocybin-Assisted Psychotherapy for Veterans With PTSD

Not yet recruitingNCT07792538

ARQ National Psychotrauma CentrePosttraumatic Stress Disorder (PTSD)

Start: 2026-12-01End: 2028-12-01Target: 12Updated: 2026-08-28

Unknown Phase

Psilocybin-assisted Interpersonal Therapy for Depression

CompletedNCT05581797

University of OtagoDepressive Disorder, Treatment-Resistant

Start: 2023-03-15End: 2024-06-04Updated: 2025-04-09