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Psilocybin 25 mg

DRUG11 trials

Sponsors

Centre for Addiction and Mental Health, Usona Institute, University of Virginia, NYU Langone Health, Nathan Brashares Sackett

Conditions

Alcohol Use Disorder (AUD)Chronic Low Back Pain (CLBP)Chronic PainDepressive Disorder, MajorIBS - Irritable Bowel SyndromeMajor Depressive Disorder (MDD)Methamphetamine Use DisorderPTSD

Early Phase 1

Phase 2

Does Psilocybin Require Psychedelic Effects to Treat Depression?
CompletedNCT05710237
Centre for Addiction and Mental HealthTreatment-resistant Depression
Start: 2023-07-01End: 2026-04-14Updated: 2026-05-07
Imaging the Effects of Serotonin 2A Receptor Modulation on Synaptic Density in Treatment-resistant Depression (SYNVEST)
RecruitingNCT06512220
Centre for Addiction and Mental HealthTreatment Resistant Depression
Start: 2025-04-21End: 2027-09-30Target: 12Updated: 2025-05-04
Treatment With Psilocybin for Chronic Neuropathic Pain and Depression (TRANSCEND)
RecruitingNCT06518720
Centre for Addiction and Mental HealthChronic Pain, Treatment Resistant Depression
Start: 2025-04-01End: 2027-12-31Target: 16Updated: 2025-04-25
Psilocybin With Psychological Support (Psi-PS) for Military Veterans and First Responders With Co-occurring PTSD & Alcohol Use Disorder (AUD)
RecruitingNCT06853912
Nathan Brashares SackettAlcohol Use Disorder (AUD), PTSD
Start: 2025-06-01End: 2026-06-01Target: 40Updated: 2025-08-28
Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD
RecruitingNCT06902974
Sunstone MedicalPost Traumatic Stress Disorder, PTSD
Start: 2026-04-01End: 2028-05-01Target: 70Updated: 2026-05-15
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
Not yet recruitingNCT07306364
Yale UniversityChronic Low Back Pain (CLBP), Physical Therapy, Psilocybin
Start: 2026-06-30End: 2029-06-30Target: 45Updated: 2025-12-29
Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use Disorder
Not yet recruitingNCT07405606
Centre for Addiction and Mental HealthAlcohol Use Disorder (AUD), Major Depressive Disorder (MDD)
Start: 2026-03-01End: 2028-06-01Target: 30Updated: 2026-02-12

Phase 3