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protamine

DRUG3 trials

Sponsors

Astrazeneca AB, Astrazeneca AB, The Medicines Company, Mustafa Kemal University

Conditions

Cardiac SurgeryCoronary Artery Bypass SurgeryProtamine Adverse ReactionProtamine AllergyReversal of anticoagulation effect in patients on a FXa inhibitor (apixabanand who have a major risk of bleeding.or edoxaban) who require urgent surgery or procedurerivaroxaban

Phase 3

Comparing Angiomax to Heparin With Protamine Reversal in Patients OPCAB
CompletedNCT00073593
The Medicines CompanyCardiac Surgery, Coronary Artery Bypass Surgery
Start: 2003-08-31Updated: 2011-11-10
A Randomized Study of Andexanet Alfa Compared to Usual Care in Patients Receiving a Factor Xa Inhibitor who Require Urgent Surgery or Procedure (ANNEXA-RS)
CompletedCTIS2022-501353-37-00
Astrazeneca AB, Astrazeneca ABand who have a major risk of bleeding., or edoxaban) who require urgent surgery or procedure, Reversal of anticoagulation effect in patients on a FXa inhibitor (apixaban +1
End: 2024-06-13Target: 467Updated: 2024-02-19

Unknown Phase

Serum Tryptase Levels During Cardiac Surgery, Diagnosis and Treatment Decisions for Allergic Reactions
CompletedNCT02644785
Mustafa Kemal UniversityProtamine Adverse Reaction, Protamine Allergy
Start: 2016-01-31End: 2016-02-29Updated: 2017-03-22