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DRUG2 trials

Sponsors

Instytut Hematologii I Transfuzjologii, Innocare Pharma Inc.

Conditions

Diffuse large B-cell lymphoma) and aggressive B-cell lymphomas (HGBCLDiffuse large B-cell lymphomas (DLBCLHigh-grade B-cell lymphoma) originate from mature B-cells at various stages of terminal differentiationTreatment-naїve mantle cell lymphoma (MCL)

Phase 2

A phase II efficacy and safety study of cell-free circulating tumor DNA-guided commencement of second-line treatment in patients with DLBCL/HGBCL relapse
Not yet recruitingCTIS2024-518275-64-00
Instytut Hematologii I TransfuzjologiiDiffuse large B-cell lymphoma) and aggressive B-cell lymphomas (HGBCL, Diffuse large B-cell lymphomas (DLBCL, High-grade B-cell lymphoma) originate from mature B-cells at various stages of terminal differentiation
Target: 340Updated: 2025-11-24

Phase 3

A Randomized, Double-Blind, Multicenter, Placebo-Controlled Phase 3 Study of Orelabrutinib in Combination with Rituximab and Bendamustine (BR) vs. BR in Subjects with Treatment-Naїve Mantle Cell Lymphoma
Not yet recruitingCTIS2025-524241-27-00
Innocare Pharma Inc.Treatment-naїve mantle cell lymphoma (MCL)
Target: 40Updated: 2026-06-01