Prolonged Exposure (PE)

BEHAVIORAL8 trials

Conditions

PTSDPost Traumatic Stress DisorderPost-Traumatic Stress DisorderPosttraumatic Stress DisorderPosttraumatic Stress Disorder (PTSD)Stress Disorders, Post-TraumaticTraumatic Brain Injury

Phase 2

Prolonged Exposure Therapy for Post Traumatic Stress Disorder Following Sexual Assault

CompletedNCT00057629

University of PennsylvaniaStress Disorders, Post-Traumatic

Start: 2002-01-31End: 2009-08-31Updated: 2015-11-13

RECONsolidation of Traumatic Memories to ResOLve Post Traumatic Stress Disorder (RECONTROLPTSD)

CompletedNCT03827057

Uniformed Services University of the Health SciencesPosttraumatic Stress Disorder, Traumatic Brain Injury

Start: 2019-06-12End: 2025-05-06Updated: 2025-07-15

Phase 3

Optimizing Posttraumatic Stress Disorder Treatment: Prolonged Exposure (PE) Versus PE Plus Sertraline

CompletedNCT01600456

Case Western Reserve UniversityPosttraumatic Stress Disorder

Start: 2011-03-31End: 2017-01-31Updated: 2021-08-03

Unknown Phase

fMRI Predictors of Treatment Response in Posttraumatic Stress Disorder (PTSD)

CompletedNCT01576510

Research Foundation for Mental Hygiene, Inc.Posttraumatic Stress Disorder (PTSD)

Start: 2010-08-31End: 2014-06-30Updated: 2014-06-24

Comparative Effectiveness Research in Veterans With PTSD

CompletedNCT01928732

VA Office of Research and DevelopmentPost-Traumatic Stress Disorder

Start: 2014-10-31End: 2019-04-18Updated: 2022-02-02

Enhancing PTSD Treatment Outcomes by Improving Patient-Provider Communication

RecruitingNCT06088303

Boston UniversityStress Disorders, Post-Traumatic

Start: 2025-01-15End: 2028-12-01Target: 54Updated: 2026-04-01

A Hybrid 1 Effectiveness-Implementation Trial of Partner-Assisted Prolonged Exposure for PTSD

RecruitingNCT06990191

United States Department of DefensePost Traumatic Stress Disorder

Start: 2025-05-16End: 2028-08-31Target: 420Updated: 2026-09-11

Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)

RecruitingNCT07176273

The University of Texas Health Science Center at San AntonioPosttraumatic Stress Disorder, PTSD

Start: 2025-12-12End: 2028-08-14Target: 302Updated: 2025-12-19

Related Papers

Reciprocal relationships between posttraumatic stress disorder symptoms and positive and negative affect in evidence-based treatments for posttraumatic stress disorder.

2024-09-01

Within-patient association between emotion regulation and outcome in prolonged exposure for posttraumatic stress disorder.

2023-11-164 citations

Comparison of Prolonged Exposure vs Cognitive Processing Therapy for Treatment of Posttraumatic Stress Disorder Among US Veterans

JAMA Network Open2022-01-19151 citations