Prochlorperazine

DRUG16 trials

Sponsors

National Cancer Institute (NCI), Gary Morrow, Montefiore Medical Center, Joseph Roscoe, Emory University

Conditions

Anaplastic Large-Cell LymphomaBreast CarcinomaBurkitt LymphomaCarcinoma In SituCervical Intraepithelial NeoplasiaDiffuse Large B-Cell Lymphoma (DLBCL)Granulosa Cell Ovarian CancerGray Zone Lymphoma

Early Phase 1

Melphalan on Disease Burden Measured by Next Generation Sequencing Before AHCT (Autologous Hematopoietic Cell Transplant) for Multiple Myeloma

WithdrawnNCT05013437

Koen van BesienMultiple Myeloma

Start: 2023-09-30End: 2024-03-31Updated: 2024-04-02

Phase 1

TRC102 and Temozolomide for Relapsed Solid Tumors and Lymphomas

CompletedNCT01851369

National Cancer Institute (NCI)Granulosa Cell Ovarian Cancer, Lymphomas, Metastatic Colon Carcinoma +2

Start: 2013-07-12End: 2023-08-01Updated: 2024-05-08

E7 TCR T Cells for Human Papillomavirus-Associated Cancers

CompletedNCT02858310

National Cancer Institute (NCI)Carcinoma In Situ, Cervical Intraepithelial Neoplasia, Papillomavirus Infections +2

Start: 2017-01-27End: 2025-07-02Updated: 2026-03-09

Phase 2

Dose-Adjusted EPOCH Chemotherapy and Rituximab (CD20+) in Previously Untreated Aggressive Non-Hodgkin's Lymphoma

CompletedNCT00001337

National Cancer Institute (NCI)Anaplastic Large-Cell Lymphoma, Burkitt Lymphoma, Diffuse Large B-Cell Lymphoma (DLBCL) +2

Start: 1993-05-08End: 2024-05-24Updated: 2025-06-22

Ondansetron vs Prochlorperazine for Nausea and Vomiting in the Emergency Department

CompletedNCT00590317

Emory UniversityNausea and Vomiting

Start: 2005-03-31End: 2008-09-30Updated: 2014-05-19

Sunitinib or Cediranib for Alveolar Soft Part Sarcoma

CompletedNCT01391962

National Cancer Institute (NCI)Sarcoma, Alveolar Soft Part

Start: 2011-07-18End: 2026-01-16Updated: 2026-02-02

Intranasal Ketorolac Trial

TerminatedNCT06083571

Washington University School of MedicineHeadache, Migraine

Start: 2024-01-01End: 2025-12-31Updated: 2026-01-16

Phase 3

Comparison of Antiemetic Drugs in Preventing Delayed Nausea After Chemotherapy in Patients With Cancer

CompletedNCT00020657

Gary MorrowNausea and Vomiting, Unspecified Adult Solid Tumor, Protocol Specific

Start: 2001-07-31End: 2004-10-31Updated: 2015-10-15

Prevention of Delayed Nausea A Phase III Double-Blind Placebo-Controlled Clinical Trial

CompletedNCT00475085

Joseph RoscoeNausea

Start: 2006-12-31Updated: 2015-11-10

Buccal Prochlorperazine Versus Intravenous Prochlorperazine for Migraine Headaches, a RCT

Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterMigraine Disorders

Start: 2016-04-30End: 2018-04-30Updated: 2018-01-05

Treatment of Refractory Nausea and Vomiting in Patients With Breast Cancer

CompletedNCT03367572

University of Rochester NCORP Research BaseBreast Carcinoma

Start: 2018-04-19End: 2024-04-13Updated: 2025-09-25

Phase 4

Prochlorperazine vs Metoclopramide

CompletedNCT00364806

Montefiore Medical CenterMigraine

Start: 2006-08-31End: 2007-03-31Target: 76Updated: 2018-04-17

Hydromorphone Versus Prochlorperazine + Diphenhydramine for Acute Migraine

CompletedNCT02389829

Montefiore Medical CenterMigraine

Start: 2015-03-31End: 2016-10-31Updated: 2018-08-31

The CHECK Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine

CompletedNCT02657031

University Medical Center of Southern NevadaHeadache

Start: 2016-03-17End: 2017-03-21Updated: 2017-12-11

Unknown Phase

Family Intervention in Recent Onset Schizophrenia Treatment (FIRST)

CompletedNCT02600741

Janssen Scientific Affairs, LLCSchizophrenia

Start: 2015-07-24End: 2018-07-05Updated: 2019-01-23

Intravenous Fluids in Pediatric Migraine

Dayton Children's HospitalMigraine, Migraine in Children

Start: 2023-06-27End: 2025-06-30Target: 134Updated: 2023-12-26

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