Primaquine Phosphate

DRUG4 trials

Sponsors

University of California, San Francisco, University of Mississippi, Oxford, London School of Hygiene and Tropical Medicine

Conditions

Glucose 6 Phosphate Dehydrogenase DeficiencyMalariaMalaria,FalciparumPlasmodium Falciparum Malaria

Phase 1

Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers Receiving a Seven Day Dose Regimen

CompletedNCT03934450

University of Mississippi, OxfordGlucose 6 Phosphate Dehydrogenase Deficiency, Malaria

Start: 2018-08-17End: 2019-05-01Updated: 2019-05-14

Phase 2

Gametocytocidal and Transmission-blocking Efficacy of PQ in Combination With AL and TQ in Combination With SPAQ in Mali

CompletedNCT05081089

London School of Hygiene and Tropical MedicineMalaria,Falciparum

Start: 2021-10-12End: 2022-01-13Updated: 2022-01-18

Gametocytocidal and Transmission-blocking Efficacy of ASAQ and ALAQ With or Without PQ in Mali

CompletedNCT05550909

London School of Hygiene and Tropical MedicineMalaria,Falciparum

Start: 2022-10-17End: 2023-01-26Updated: 2024-10-01

Phase 4

Targeted Active Case Detection Among High Risk Populations in Southern Lao Peoples Democratic Republic

CompletedNCT03783299

University of California, San FranciscoPlasmodium Falciparum Malaria

Start: 2017-11-28End: 2018-12-31Updated: 2021-02-23

Related Papers

Artemether-lumefantrine-amodiaquine or artesunate-amodiaquine combined with single low-dose primaquine to reduce Plasmodium falciparum malaria transmission in Ouélessébougou, Mali: a five-arm, phase 2, single-blind, randomised controlled trial.

2024-12-177 citations

Artemether-lumefantrine with or without single-dose primaquine and sulfadoxine-pyrimethamine plus amodiaquine with or without single-dose tafenoquine to reduce Plasmodium falciparum transmission: a phase 2, single-blind, randomised clinical trial in Ouelessebougou, Mali.

2024-05-0211 citations

Study protocol for a cluster-randomized split-plot design trial to assess the effectiveness of targeted active malaria case detection among high-risk populations in Southern Lao PDR (the AcME-Lao study).

2019-12-1711 citations