Preparative Regimen

DRUG5 trials

Conditions

Acute Myelogenous LeukemiaAcute Myeloid LeukemiaDisorder Related to TransplantationHematologic MalignanciesHematopoietic MalignancyJuvenile Myelomonocytic LeukemiaMyelodysplastic SyndromeRefractory Acute Lymphoblastic Leukemia

Phase 1

Stem Cell Transplant for Juvenile Myelomonocytic Leukemia (JMML)

CompletedNCT00167219

Masonic Cancer Center, University of MinnesotaJuvenile Myelomonocytic Leukemia

Start: 1999-11-18End: 2023-08-09Updated: 2023-11-07

Haploidentical Donor Natural Killer Cell Infusion With IL-15 in Acute Myelogenous Leukemia (AML)

CompletedNCT01385423

Masonic Cancer Center, University of MinnesotaAcute Myelogenous Leukemia, Myelodysplastic Syndrome

Start: 2011-09-30End: 2015-03-31Updated: 2025-07-24

Phase 2

Umbilical Cord Blood Transplantation In Patients With Hematologic Malignancies Using A Myeloablative Preparative Regimen

CompletedNCT01328496

St. Jude Children's Research HospitalDisorder Related to Transplantation, Hematologic Malignancies, Hematopoietic Malignancy

Start: 2011-06-15End: 2016-10-31Updated: 2017-06-05

NK Cell Based Non-Myeloablative Transplantation in Acute Myeloid Diseases

CompletedNCT01370213

Masonic Cancer Center, University of MinnesotaAcute Myeloid Leukemia, Myelodysplastic Syndrome

Start: 2011-09-30End: 2017-04-30Updated: 2020-05-13

Phase 3

Personalized Targeted Preparative Regimen Before T-depleted Allogeneic HSCT in Children With Chemoresistent Acute Leukemias

NCT04000698

Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyRefractory Acute Lymphoblastic Leukemia, Refractory Acute Myeloid Leukemia

Start: 2019-10-15End: 2022-12-31Target: 25Updated: 2020-11-20

Related Papers

IL-15 in the Combination Immunotherapy of Cancer.

2020-05-19183 citations

First-in-human trial of rhIL-15 and haploidentical natural killer cell therapy for advanced acute myeloid leukemia