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Pregabalin 300 mg
DRUG
5 trials
Sponsors
Pfizer
, Hamilton Health Sciences Corporation
, Latigo Biotherapeutics
Conditions
Chronic pain
Diabetic Neuropathy, Painful
Healthy
Opioid Use
Pain Detection
Pain Threshold
Early Phase 1
Pharmacodynamic Study of 300mg Pregabalin vs Placebo in Healthy Male Adults
Completed
NCT06600607
Latigo Biotherapeutics
Pain Detection, Pain Threshold
Start: 2024-10-07
End: 2024-10-27
Updated: 2025-05-04
Phase 1
Assessment of the Analgesic Effects of PF-05089771 and Pregabalin in Healthy Volunteers Using Evoked Pain Endpoints
Completed
NCT02349607
Pfizer
Healthy
Start: 2015-01-31
End: 2015-03-31
Updated: 2015-04-23
Phase 2
A Clinical Trial To Evaluate PF-05089771 On Its Own And As An Add-On Therapy To Pregabalin (Lyrica) For The Treatment Of Pain Due To Diabetic Peripheral Neuropathy (DPN)
Completed
NCT02215252
Pfizer
Diabetic Neuropathy, Painful
Start: 2014-11-10
End: 2015-09-28
Updated: 2017-05-05
Phase 3
Perioperative Pregabalin for Reducing Opioid Consumption After Cardiac Surgery
Terminated
NCT04517110
Hamilton Health Sciences Corporation
Opioid Use
Start: 2021-04-09
End: 2022-09-07
Updated: 2022-09-10
Unknown Phase
A double blind, double dummy, randomized, placebo-controlled, 5 period cross-over study to examine the effect of PF-05089771 alone and in combination with pregabalin on evoked pain endpoints in healthy volunteers using pregabalin and ibuprofen as positive controls
Active, not recruiting
NL-OMON42223
Pfizer
Chronic pain
Start: 2015-01-19
Target: 25
Updated: 2024-04-23
Related Papers
Lack of Detection of the Analgesic Properties of PF‐05089771, a Selective Na<sub>v</sub>1.7 Inhibitor, Using a Battery of Pain Models in Healthy Subjects
Clinical and Translational Science
2019-10-23
52 citations
Efficacy of the Nav1.7 blocker PF-05089771 in a randomised, placebo-controlled, double-blind clinical study in subjects with painful diabetic peripheral neuropathy
Pain
2018-03-23
158 citations