pravastatin sodium

DRUG13 trials

Sponsors

National Institute of Allergy and Infectious Diseases (NIAID), Bristol-Myers Squibb, University College, London, Teva Pharmaceuticals USA, SWOG Cancer Research Network

Conditions

Actue Coronary SyndromesAdult Acute Megakaryoblastic Leukemia (M7)Adult Acute Minimally Differentiated Myeloid Leukemia (M0)Adult Acute Monoblastic Leukemia (M5a)Adult Acute Monocytic Leukemia (M5b)Adult Acute Myeloblastic Leukemia With Maturation (M2)Adult Acute Myeloblastic Leukemia Without Maturation (M1)Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities

Phase 1

A Study on Possible Interactions Between Protease Inhibitors (Anti-HIV Drugs) and Drugs Which Lower the Level of Fat in Your Blood

CompletedNCT00000941

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections

End: 2002-03-31Target: 56Updated: 2021-10-29

The Effect of Efavirenz and Nelfinavir on the Blood Levels of Certain Lipid-Lowering Drugs

CompletedNCT00017758

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, HIV Seronegativity, Lipodystrophy

Target: 56Updated: 2006-03-14

Bioavailability Study of Pravastatin Sodium 40 mg Tablets Under Fasting Conditions

CompletedNCT00834379

Teva Pharmaceuticals USAHealthy

Start: 2000-09-30End: 2000-09-30Updated: 2020-10-08

Bioequivalence Study of Pravastatin Sodium Tablets 80 mg Under Fed Conditions

CompletedNCT01146093

Dr. Reddy's Laboratories LimitedHealthy

Start: 2002-11-30End: 2003-03-31Updated: 2012-01-13

Bioequivalence Study of Pravastatin Sodium Tablets 80 mg Under Fasting Conditions

CompletedNCT01146106

Dr. Reddy's Laboratories LimitedHealthy

Start: 2002-12-31End: 2002-12-31Updated: 2010-06-17

Cyclosporine, Pravastatin Sodium, Etoposide, and Mitoxantrone Hydrochloride in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

TerminatedNCT01342887

Fred Hutchinson Cancer CenterAdult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a) +12

Start: 2011-04-30End: 2012-03-31Updated: 2017-07-02

Phase 2

S0919 Idarubicin, Cytarabine, and Pravastatin in Treating Patients With Relapsed Acute Myeloid Leukemia

CompletedNCT00840177

SWOG Cancer Research NetworkLeukemia

Start: 2009-12-10End: 2021-10-21Updated: 2023-05-03

Effect of HAART Vs. Statin Treatment on Endothelial Function and Inflammation/Coagulation

WithdrawnNCT01515813

Advancing Clinical Therapeutics Globally for HIV/AIDS and Other InfectionsHIV-1 Infection

Start: 2011-11-30End: 2014-12-31Updated: 2016-02-01

Phase 3

Safety and Effectiveness of Fenofibrate and Pravastatin in HIV-Positive Patients With Abnormal Blood Lipids

CompletedNCT00006412

National Institute of Allergy and Infectious Diseases (NIAID)HIV Infections, Lipodystrophy

End: 2003-05-31Target: 630Updated: 2021-11-01

Etoposide and Cisplatin or Carboplatin as First-Line Chemotherapy With or Without Pravastatin in Treating Patients With Small Cell Lung Cancer

CompletedNCT00433498

University College, LondonLung Cancer

Start: 2007-01-31End: 2013-11-30Updated: 2014-12-03

Sorafenib Tosylate With or Without Pravastatin in Treating Patients With Liver Cancer and Cirrhosis

CompletedNCT01075555

Federation Francophone de Cancerologie DigestiveLiver Cancer

Start: 2010-02-28End: 2015-09-30Updated: 2020-03-30

Phase 4

Pravastatin or Atorvastatin Evaluation and Infection Therapy (TIMI22)

CompletedNCT00382460

Bristol-Myers SquibbActue Coronary Syndromes

Start: 2000-11-30End: 2003-12-31Target: 4000Updated: 2011-04-15

Unknown Phase

Idarubicin, Cytarabine, and Pravastatin Sodium in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes

CompletedNCT01831232

Fred Hutchinson Cancer CenterAdult Acute Megakaryoblastic Leukemia (M7), Adult Acute Minimally Differentiated Myeloid Leukemia (M0), Adult Acute Monoblastic Leukemia (M5a) +16

Start: 2013-05-31End: 2016-01-31Updated: 2017-11-17

Related Papers

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Pravastatin combination with sorafenib does not improve survival in advanced hepatocellular carcinoma.

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Comparable outcomes of patients eligible vs ineligible for SWOG leukemia studies

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What is the optimal blood pressure in patients after acute coronary syndromes?: Relationship of blood pressure and cardiovascular events in the PRavastatin OR atorVastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction (PROVE IT-TIMI) 22 trial.

2010-11-08160 citations

Effect of intensive statin therapy on clinical outcomes among patients undergoing percutaneous coronary intervention for acute coronary syndrome. PCI-PROVE IT: A PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22) Substudy.

2009-12-0194 citations

Baseline low-density lipoprotein cholesterol is an important predictor of the benefit of intensive lipid-lowering therapy: a PROVE IT-TIMI 22 (Pravastatin or Atorvastatin Evaluation and Infection Therapy-Thrombolysis In Myocardial Infarction 22) analysis.

2008-09-0153 citations