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Prasterone

DRUG5 trials

Sponsors

Mayo Clinic, Alliance for Clinical Trials in Oncology, San Diego Sexual Medicine, Olivia Cardenas-Trowers, M.D., Ohio State University Comprehensive Cancer Center

Conditions

Anal CarcinomaBreast CancerCervical CarcinomaDyspareuniaGynecologic CancerMalignant Female Reproductive System NeoplasmMenopauseMultiple Myeloma and Plasma Cell Neoplasm

Phase 2

Chemoprevention Therapy in Treating Patients at High Risk of Developing Multiple Myeloma
CompletedNCT00006219
Mayo ClinicMultiple Myeloma and Plasma Cell Neoplasm
Start: 2000-08-31End: 2006-12-31Updated: 2011-08-04
Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer
RecruitingNCT07407647
Ohio State University Comprehensive Cancer CenterAnal Carcinoma, Cervical Carcinoma, Malignant Female Reproductive System Neoplasm +3
Start: 2026-03-12End: 2026-12-31Target: 25Updated: 2026-04-21

Phase 3

Prasterone (Dehydroepiandrosterone) in Treating Postmenopausal Cancer Survivors With Vaginal Symptoms
CompletedNCT01376349
Alliance for Clinical Trials in OncologyBreast Cancer, Gynecologic Cancer
Start: 2011-07-31End: 2017-11-30Updated: 2019-02-07
Clinical Trial on the Preventive Effect of Intravaginal Prasterone on Recurrent Urinary Tract Infections in Postmenopausal Women
WithdrawnNCT03854396
Olivia Cardenas-Trowers, M.D.Menopause, Postmenopausal Symptoms, Postmenopausal Syndrome +2
Start: 2020-05-31End: 2021-02-28Updated: 2021-06-30

Phase 4

Changes to Vulva, Vestibule, Urethral Meatus and Vagina 20 Weeks Post Daily Prasterone in Women With Dyspareunia
CompletedNCT03568604
San Diego Sexual MedicineDyspareunia
Start: 2018-08-07End: 2020-01-28Updated: 2022-06-09

Related Papers

Impact of vaginal dehydroepiandosterone (DHEA) on vaginal symptoms in female cancer survivors: Trial N10C1 (Alliance).
Journal of Clinical Oncology2014-05-2013 citations