Pralsetinib
Sponsors
Hoffmann-La Roche, Genentech, Inc., Fondazione per la Medicina Personalizzata, Seoul National University Bundang Hospital, West China Hospital
Conditions
AdenocarcinomaAdvanced Solid TumorAdvanced Unresectable or Metastatic Solid MalignancyBreast CancerBronchial DiseasesCarcinomaCarcinoma, BronchogenicCarcinoma, Non-Small-Cell Lung
Phase 2
A Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)
RecruitingNCT04302025
Start: 2020-11-06End: 2030-05-30Target: 99Updated: 2026-04-03
Tumor-agnostic Precision Immuno-oncology and Somatic Targeting Rational for You (TAPISTRY) Platform Study
Active, not recruitingNCT04589845
Start: 2021-01-18End: 2032-09-25Target: 920Updated: 2026-04-02
The Rome Trial From Histology to Target: the Road to Personalize Target Therapy and Immunotherapy
NCT04591431
Start: 2020-10-07End: 2025-06-30Updated: 2023-10-03
A Study Evaluating Targeted Therapies in Participants Who Have Advanced Solid Tumors With Genomic Alterations or Protein Expression Patterns Predictive of Response
CompletedNCT04632992
Start: 2021-01-13End: 2024-02-27Updated: 2025-01-08
Efficacy of Organoid-Based Drug Screening to Guide Treatment for Locally Advanced Thyroid Cancer
RecruitingNCT06482086
Start: 2021-06-01End: 2025-12-01Target: 75Updated: 2024-12-05
Neoadjuvant Umbrella Trial for Patients With Unresectable Stage III NSCLC Harboring Rare Mutations.
RecruitingNCT06563999
Start: 2024-11-01End: 2029-11-01Target: 120Updated: 2024-12-10
Phase 3
A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC)
TerminatedNCT04222972
Start: 2020-07-24End: 2025-01-27Updated: 2026-03-05
A Study of Pralsetinib Versus Standard of Care (SOC) for Treatment of RET-Mutated Medullary Thyroid Cancer (MTC).
WithdrawnNCT04760288
Start: 2023-11-30End: 2035-04-12Updated: 2024-01-05
Phase 4
Unknown Phase
KPMNG Study of MOlecular Profiling Guided Therapy Based on Genomic Alterations in Advanced Solid Tumors II
RecruitingNCT05525858
Start: 2022-09-28End: 2027-03-31Target: 1000Updated: 2025-04-27
A Real-world Study of Pralsetinib Combined With Leucogen in the Treatment of RET Fusion-positive NSCLC
Not yet recruitingNCT07418879
Start: 2026-02-05End: 2028-12-31Target: 25Updated: 2026-02-18
Related Papers
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