FindTrial
Sign In

Poractant alfa

DRUG8 trials

Sponsors

Dr. Sami Ulus Children's Hospital, Chiesi Farmaceutici S.p.A., University of Missouri-Columbia, Hospital Central Dr. Ignacio Morones Prieto, Dr Christophe LENCLUD

Conditions

ARDS, HumanBronchopulmonary DysplasiaCOVID-19Infant,PrematurePoor Peripheral PerfusionPremature BirthPulmonary HemorrhageRespiratory Distress Syndrome

Phase 2

A Double Blind, Randomized, Controlled Study to Evaluate CHF 5633 (Synthetic Surfactant) and Poractant Alfa in Neonates With Respiratory Distress Syndrome (RDS) (POC)
CompletedNCT02452476
Chiesi Farmaceutici S.p.A.Respiratory Distress Syndrome, Newborn
Start: 2016-01-21End: 2018-05-24Updated: 2021-08-13
Curosurf® in Adult Acute Respiratory Distress Syndrome Due to COVID-19
NCT04384731
Dr Christophe LENCLUDARDS, Human, COVID-19
Start: 2020-05-29End: 2021-07-31Target: 20Updated: 2021-02-03

Phase 4

Efficacy of Adding Budesonide to Poractant Alfa to Prevent Bronchopulmonary Dysplasia.
NCT03521063
Hospital Central Dr. Ignacio Morones PrietoBronchopulmonary Dysplasia, Infant,Premature, Respiratory Distress Syndrome
Start: 2018-01-01End: 2019-12-31Target: 108Updated: 2019-08-07
Prophylactic Minimally Invasive Surfactant Evaluation
RecruitingNCT06007547
Endeavor HealthPremature Birth, Respiratory Distress Syndrome, Newborn
Start: 2024-01-01End: 2027-07-31Target: 200Updated: 2025-08-07
Calfactant vs Poractant Alfa Using a Less Invasive Technique in Preterm Infants With Respiratory Distress Syndrome
RecruitingNCT07350018
Uludag UniversityRespiratory Distress Syndrome in Premature Infants, Respiratory Distress Syndrome (RDS), Surfactant
Start: 2026-01-20End: 2027-02-20Target: 234Updated: 2026-04-28

Unknown Phase

Perfusion Index Variability in Respiratory Distress Syndrome
CompletedNCT01852461
Dr. Sami Ulus Children's HospitalPoor Peripheral Perfusion
Start: 2011-08-31End: 2012-12-31Updated: 2013-05-13
Comparison of Two Different Natural Surfactants in the Treatment of Pulmonary Hemorrhage
CompletedNCT01860014
Dr. Sami Ulus Children's HospitalPulmonary Hemorrhage
Start: 2010-03-31End: 2011-03-31Updated: 2013-05-22
Comparison of Curosurf and Infasurf in the Treatment of Preterm Infants With Respiratory Distress Syndrome
CompletedNCT02834624
University of Missouri-ColumbiaRespiratory Distress Syndrome
Start: 2013-07-31End: 2015-07-31Updated: 2017-06-06

Related Papers

Synthetic Surfactant CHF5633 Compared with Poractant Alfa in the Treatment of Neonatal Respiratory Distress Syndrome: A Multicenter, Double-Blind, Randomized, Controlled Clinical Trial.
2020-06-1428 citations
A first-in-human clinical study of a new SP-B and SP-C enriched synthetic surfactant (CHF5633) in preterm babies with respiratory distress syndrome
Archives of Disease in Childhood Fetal & Neonatal2017-05-0271 citations