Polymyxin B

DRUG7 trials

Conditions

Acinetobacter Baumannii-calcoaceticus ComplexAntibiotic Resistant InfectionAntibiotic ToxicityBacteremiaColistin Resistanrt ABCCritical IllnessHealthcare-associated PneumoniaHospital Acquired Bacterial Pneumonia (HABP)

Early Phase 1

The Combined Antibiotic Therapy for Carbapenem Resistant Klebsiella Pneumoniae

NCT03950544

Shanghai 10th People's HospitalAntibiotic Resistant Infection

Start: 2019-01-01End: 2020-12-31Target: 80Updated: 2019-05-15

Phase 1

A Pharmacokinetic Study of Polymyxin B in Healthy Subjects and Subjects With Renal Insufficiency

CompletedNCT05359627

TTY BiopharmAntibiotic Toxicity

Start: 2022-07-26End: 2023-03-03Updated: 2023-04-27

Phase 2

Randomized-controlled Trial (RCT) on Combination Antibiotic for Infections Caused by Gram-negative Bacteria

WithdrawnNCT02134106

Tan Tock Seng HospitalBacteremia, Healthcare-associated Pneumonia, Ventilator-associated Pneumonia

Start: 2015-01-31End: 2015-12-31Updated: 2019-10-09

Phase 3

Polymyxin B Monotherapy vs Combination Therapy in Critically Ill Patients With Multi-drug Resistant Pathogens

NCT03159078

University of Puerto RicoCritical Illness, Resistant Infection, Trauma

Start: 2017-05-25End: 2019-12-01Target: 40Updated: 2019-02-08

Efficacy and Safety of BV100 Plus Low Dose Polymyxin B Versus Colistin Plus High-dose Ampicillin/Sulbactam in Patients With Hospital-acquired or Ventilator-associated Bacterial Pneumonia Due to Carbapenem-resistant Acinetobacter Baumannii-calcoaceticus Complex

Not yet recruitingNCT07326540

BioVersys SASAcinetobacter Baumannii-calcoaceticus Complex, Colistin Resistanrt ABC, Hospital Acquired Bacterial Pneumonia (HABP) +1

Start: 2026-03-20End: 2028-03-30Target: 248Updated: 2026-01-08

Phase 4

Efficacy of Polymyxin B Against Infections Caused by Extensively Drug-resistant (XDR) Gram-Negative Bacteria

NCT02328183

Mahidol UniversityHospital Infection

Start: 2014-12-31End: 2015-11-30Target: 100Updated: 2015-09-01

Unknown Phase

Intraventricular Administration of Intracranial Infections Caused by （Carbapenem-resistant Gram-negative Bacilli）CRGNB

RecruitingNCT06595979

Second Affiliated Hospital, School of Medicine, Zhejiang UniversityIntracranial Infections

Start: 2024-06-25End: 2026-12-31Target: 222Updated: 2024-09-19

Related Papers

The Genomic Characterization of KPC-Producing Klebsiella pneumoniae from the ICU of a Teaching Hospital in Shanghai, China

Infection and Drug Resistance2022-01-014 citations