pleurectomy/decortication

PROCEDURE4 trials

Sponsors

Brigham and Women's Hospital, Memorial Sloan Kettering Cancer Center, European Organisation for Research and Treatment of Cancer - EORTC, Papworth Hospital NHS Foundation Trust

Conditions

Malignant Pleural MesotheliomaMesotheliomaTrapped Lung

Phase 1

Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesothelioma

CompletedNCT00571298

Brigham and Women's HospitalMalignant Pleural Mesothelioma

Start: 2007-11-30End: 2015-06-30Updated: 2017-01-23

Phase 2

Pleurectomy/Decortication (Neo) Adjuvant Chemotherapy and Intensity Modulated Radiation Therapy to the Pleura in Patients With Locally Advanced Malignant Pleural Mesothelioma

Active, not recruitingNCT00715611

Memorial Sloan Kettering Cancer CenterMesothelioma

Start: 2008-10-11End: 2026-07-31Updated: 2025-08-15

Pleurectomy/ Decortication (P/D) Preceded or Followed by Chemotherapy in Patients With Early Stage MPM

European Organisation for Research and Treatment of Cancer - EORTCMalignant Pleural Mesothelioma

Start: 2016-09-20End: 2023-09-30Target: 64Updated: 2022-11-07

Unknown Phase

MesoTRAP: A Study Comparing Video-assisted Thoracoscopic Partial Pleurectomy/Decortication With Indwelling Pleural Catheter in Patients With Trapped Lung Due to Malignant Pleural Mesothelioma.

CompletedNCT03412357

Papworth Hospital NHS Foundation TrustMalignant Pleural Mesothelioma, Trapped Lung

Start: 2017-08-10End: 2020-08-01Updated: 2020-09-16

Related Papers

MesoTRAP: a feasibility study that includes a pilot clinical trial comparing video-assisted thoracoscopic partial pleurectomy decortication with indwelling pleural catheter in patients with trapped lung due to malignant pleural mesothelioma designed to address recruitment and randomisation uncertainties and sample size requirements for a phase III trial

BMJ Open Respiratory Research2019-01-0129 citations

A multicenter phase II toxicity study of lung-sparing intensity modulated radiation therapy (IMRT) for malignant pleural mesothelioma (MPM).

Journal of Clinical Oncology2014-05-201 citations