Platinum-based chemotherapy
Sponsors
New Mexico Cancer Research Alliance, Hoffmann-La Roche, University Health Network, Toronto, The Christie NHS Foundation Trust, Incyte Corporation
Conditions
Advanced Non-Small Cell Lung CancerAdvanced Solid TumorAdvanced Solid TumorsCarcinoma, Non-Small Cell LungCarcinoma, Non-Small-Cell LungCervical CancerDebulking Surgical ProceduresEGFR Exon 19 Deletion
Early Phase 1
Phase 1
Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib
RecruitingNCT04486833
Start: 2021-09-03End: 2029-03-01Target: 158Updated: 2026-01-21
NTX-301 Monotherapy in Advanced Solid Tumours and in Combination With Platinum-based Chemotherapy in Advanced Ovarian & Bladder Cancer and in Combination With Temozolomide in High-grade Glioma
TerminatedNCT04851834
Start: 2021-08-25End: 2022-11-08Updated: 2022-12-20
A First-in-human Study to Learn How Safe the Study Drug BAY2965501 is, Find the Best Dose (Single Drug & Combination), How it Affects the Body, What Maximum Amount Can be Given, How it Moves Into, Through and Out of the Body, How it Acts on Different Tumors in Participants With Advanced Solid Tumors
Active, not recruitingNCT05614102
Start: 2022-11-04End: 2027-04-14Target: 284Updated: 2026-03-31
Phase 2
Erlotinib and Standard Platinum-Based Chemotherapy for Newly Diagnosed, Advanced Non-Small Cell Carcinoma of the Lung
TerminatedNCT00391586
Start: 2006-07-31End: 2012-05-31Updated: 2015-08-17
A Study of Avastin (Bevacizumab) in Combination With Platinum-Based Chemotherapy in Patients With Advanced or Recurrent Squamous Non-Small Cell Lung Cancer
TerminatedNCT00404703
Start: 2006-08-31End: 2008-02-29Updated: 2016-08-24
A Study of Olaparib Prior to Surgery and Chemotherapy in Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
Active, not recruitingNCT02489006
Start: 2016-07-19End: 2025-12-31Target: 71Updated: 2024-01-17
A Study of Pembrolizumab Plus Epacadostat With Platinum-based Chemotherapy Versus Pembrolizumab Plus Platinum-based Chemotherapy Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-715-06/ECHO-306-06)
CompletedNCT03322566
Start: 2018-01-09End: 2020-10-16Updated: 2022-01-24
Study of Nivolumab-Ipilimumab and cfDNA in Lung Cancer
TerminatedNCT04966676
Start: 2022-01-24End: 2025-02-19Updated: 2026-01-08
A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)
RecruitingNCT06465329
Start: 2024-11-18End: 2030-05-02Target: 120Updated: 2026-02-12
A Study of Adebrelimab in Combination with Chemo with or Without Bevacizumab Neoadjuvant Therapy for Resectable NSCLC
RecruitingNCT06775275
Start: 2024-09-24End: 2029-12-31Target: 60Updated: 2025-01-15
Toripalimab Combined With Platinum-based Chemotherapy With or Without H1 Receptor Antagonist in the Perioperative Treatment of Resectable Non-small Cell Lung Cancer
Not yet recruitingNCT07358689
Start: 2026-01-30End: 2029-01-01Target: 120Updated: 2026-01-22
Phase 3
Camrelizumab Combined With Famitinib Malate for Treatment of Recurrent/Metastatic Cervical Cancer
Active, not recruitingNCT04906993
Start: 2021-07-23End: 2027-05-31Updated: 2025-09-09
HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Advanced EGFRm NSCLC After Failure of EGFR TKI Therapy
Active, not recruitingNCT05338970
Start: 2022-07-08End: 2026-06-30Updated: 2025-01-31
Study to Compare Furmonertinib to Platinum-Based Chemotherapy for Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion Mutations (FURVENT)
Active, not recruitingNCT05607550
Start: 2023-06-01End: 2028-02-15Updated: 2025-06-22
Phase 4
Unknown Phase
An Observational Study to Assess the Effectiveness and Safety of a Cemiplimab in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) in Routine Clinical Practice Settings in Europe
RecruitingNCT05363319
Start: 2022-10-26End: 2028-10-30Target: 500Updated: 2026-03-18
Retrospective, External Comparator Study of Lazertinib as the 2nd-Line Treatment in Patients With EGFR Mutation+ NSCLC
CompletedNCT05862194
Start: 2015-06-01End: 2023-03-20Updated: 2023-08-22
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