Plasmalyte

DRUG14 trials

Sponsors

Yonsei University, Brugmann University Hospital, University of British Columbia, Cliniques universitaires Saint-Luc- Université Catholique de Louvain, University Hospital Olomouc

Conditions

Acid Base ImbalanceAcute Kidney InjuryCardiopulmonary BypassCirrhosis With SepsisCongenital Heart DiseaseCrystalloid SolutionsElectrolyte ChangesFluid Resuscitation

Phase 1

A Low ChloridE hyperTonic Solution for Brain Edema

CompletedNCT03204955

Emory UniversityAcute Kidney Injury, Subarachnoid Hemorrhage

Start: 2017-06-28End: 2018-09-30Updated: 2023-05-01

Evaluation of the Protective Efficacy of TV003 or Previous Zika Infection Against Infection With ZIKV-SJRP Challenge Compared to DENV and ZIKV-naïve Controls Against Infection With ZIKV-SJRP Challenge

CompletedNCT06805487

National Institute of Allergy and Infectious Diseases (NIAID)Zika Virus

Start: 2024-09-24End: 2025-09-15Updated: 2026-03-09

Phase 3

Perioperative Fluid Therapy With Balanced Crystalloids

CompletedNCT02691676

University Hospital OlomoucAcid Base Imbalance

Start: 2014-01-31End: 2014-12-31Updated: 2017-05-09

Fluid Resuscitation in Burn Patients

CompletedNCT03118362

Assistance Publique - Hôpitaux de ParisFluid Resuscitation, Severe Burns

Start: 2017-08-09End: 2019-12-02Updated: 2019-12-13

Phase 4

Crystalloids or Colloids for Goal-directed Fluid Therapy With Closed-loop Assistance in Major Surgery

CompletedNCT02312999

Brugmann University HospitalSurgery

Start: 2015-02-24End: 2017-12-21Updated: 2018-01-19

Influence of Albumin on Acute Renal Dysfunction Associated With Cardiac Surgery Under Extracorporeal Circulation

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauAcute Kidney Injury

Start: 2018-01-10End: 2019-08-31Target: 250Updated: 2018-01-25

Unknown Phase

The Aim of This Investigation is to Compare the Influence of 0.9% Saline and Plasmalyte Solution on Acid-base Balance and Electrolytes in Healthy Patients Undergoing Major Spine Surgeries.

CompletedNCT01855542

Yonsei UniversitySpinal Surgery

Start: 2012-03-31End: 2013-01-31Updated: 2013-05-16

Effects of Goal-directed Fluid Therapy on Post-operative Outcomes in Children Undergoing Scoliosis Repair

TerminatedNCT02463175

University of British ColumbiaAcute Kidney Injury, Scoliosis

Start: 2015-06-30End: 2016-01-31Updated: 2017-10-26

Fresh Frozen Plasma and Plasmalyte ® for Priming Cardiopulmonary Bypass in Infants and Children

CompletedNCT02567786

Cliniques universitaires Saint-Luc- Université Catholique de LouvainCongenital Heart Disease

Start: 2015-10-31End: 2018-07-31Updated: 2018-12-05

Comparison of Colloid (20% Albumin) Versus Crystalloid (Plasmalyte) for Fluid Resuscitation in Cirrhotics With Sepsis Induced Hypotension.

CompletedNCT02721238

Institute of Liver and Biliary Sciences, IndiaCirrhosis With Sepsis

Start: 2016-12-01End: 2018-11-03Updated: 2021-08-26

Comparison of Ringer Lactate and Isotonic Acetate Solution as Perioperative Maintenance Fluid for Children

Post Graduate Institute of Medical Education and Research, ChandigarhHyponatremia

Start: 2016-09-30End: 2017-02-28Target: 50Updated: 2016-10-18

Efficacy of 5% Albumin v/s Plasmalyte in Combination With 20% Albumin for Fluid Resuscitation in Cirrhosis With Sepsis Induced Hypotension

Institute of Liver and Biliary Sciences, IndiaLiver Cirrhosis

Start: 2023-09-30End: 2024-08-31Target: 120Updated: 2023-10-10

To Study Effect of Injection Pentoxifylline on Liver Growth After Major Liver Surgery

RecruitingNCT07085806

Institute of Liver and Biliary Sciences, IndiaLiver Regeneration

Start: 2025-01-01End: 2025-07-31Target: 60Updated: 2025-07-25

Heart-Lung Machine: Impact of the Priming Solution on Acid-Base Balance, Electrolytes and Outcome on Patients Undergoing Cardiac Surgery

RecruitingNCT07267546

Region SkaneAcid Base Imbalance, Cardiopulmonary Bypass, Crystalloid Solutions +2

Start: 2025-09-01End: 2026-11-01Target: 80Updated: 2025-12-05

Related Papers

A randomized-controlled trial comparing 20% albumin to plasmalyte in patients with cirrhosis and sepsis-induced hypotension [ALPS trial].

2022-04-2059 citations

Low-chloride- versus high-chloride-containing hypertonic solution for the treatment of subarachnoid hemorrhage–related complications: The ACETatE (A low ChloriE hyperTonic solution for brain Edema) randomized trial

Journal of Intensive Care2020-05-0449 citations

Low-chloride versus high-chloride hypertonic solution for the treatment of subarachnoid hemorrhage-related complications (The ACETatE trial): study protocol for a pilot randomized controlled trial

Trials2018-11-1410 citations